2C-BioID: An Advanced Two Component BioID System for Precision Mapping of Protein Interactomes

Summary: The modulation of protein-protein interactions (PPIs) is an essential regulatory activity defining diverse cell functions in development and disease. BioID is an unbiased proximity-dependent biotinylation method making use of a biotin-protein ligase fused to a protein of interest and has be...

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Bibliographic Details
Main Authors: Alexandre Chojnowski, Radoslaw M. Sobota, Peh Fern Ong, Wei Xie, Xianrong Wong, Oliver Dreesen, Brian Burke, Colin L. Stewart
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S258900421830213X