Anthraquinone Content in Noni (Morinda citrifolia L.)

Noni has been used in traditional medicine and as food for thousands of years. While the fruits serve as food and internal medicine, leaves were traditionally used only topically. In recent years, concern regarding the possible content of anthraquinones in noni has led to scrutiny by the European Fo...

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Main Authors: Rainer W. Bussmann, Lothar Hennig, Athanassios Giannis, Jutta Ortwein, Toni M. Kutchan, Xi Feng
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2013/208378
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spelling doaj-bf27ac1a2d6b46ff94443d9b8ed934be2020-11-24T23:52:07ZengHindawi LimitedEvidence-Based Complementary and Alternative Medicine1741-427X1741-42882013-01-01201310.1155/2013/208378208378Anthraquinone Content in Noni (Morinda citrifolia L.)Rainer W. Bussmann0Lothar Hennig1Athanassios Giannis2Jutta Ortwein3Toni M. Kutchan4Xi Feng5William L. Brown Center, Missouri Botanical Garden, P.O. Box 299, St. Louis, MO 63166-0299, USAInstitute of Organic Chemistry, University of Leipzig, Johannisallee 29, 4103 Leipzig, GermanyInstitute of Organic Chemistry, University of Leipzig, Johannisallee 29, 4103 Leipzig, GermanyInstitute of Pharmacy, University of Leipzig, Brüderstraße 34, 4103 Leipzig, GermanyDonald Danforth Plant Science Center, 975 N. Warson Road, St. Louis, MO 63132314-587-1473, USADonald Danforth Plant Science Center, 975 N. Warson Road, St. Louis, MO 63132314-587-1473, USANoni has been used in traditional medicine and as food for thousands of years. While the fruits serve as food and internal medicine, leaves were traditionally used only topically. In recent years, concern regarding the possible content of anthraquinones in noni has led to scrutiny by the European Food Safety Authority. Little research existed on the content of anthraquinones in different noni preparations, with no information about the potential effect of harvest and preparation methods. Our research focused on lucidin, alizarin, and rubiadin, the most important anthraquinones from a health perspective. We found that the production process (fermentation/juice production versus drying/lyophilization) has no effect on the anthraquinone content. The source product, however, does have implications: noni fruit puree from which seeds had been removed as well as consumer products produced from such puree had no detectable amounts of any anthraquinones. Products that did contain seed or leaf material in all cases did contain partly significant amounts of anthraquinones. To alleviate safety concerns, we suggest that noni products, whether fermented or unfermented juice or powder, should be derived only from fully ripe noni fruits, and that any seed material needs to be removed during the production process.http://dx.doi.org/10.1155/2013/208378
collection DOAJ
language English
format Article
sources DOAJ
author Rainer W. Bussmann
Lothar Hennig
Athanassios Giannis
Jutta Ortwein
Toni M. Kutchan
Xi Feng
spellingShingle Rainer W. Bussmann
Lothar Hennig
Athanassios Giannis
Jutta Ortwein
Toni M. Kutchan
Xi Feng
Anthraquinone Content in Noni (Morinda citrifolia L.)
Evidence-Based Complementary and Alternative Medicine
author_facet Rainer W. Bussmann
Lothar Hennig
Athanassios Giannis
Jutta Ortwein
Toni M. Kutchan
Xi Feng
author_sort Rainer W. Bussmann
title Anthraquinone Content in Noni (Morinda citrifolia L.)
title_short Anthraquinone Content in Noni (Morinda citrifolia L.)
title_full Anthraquinone Content in Noni (Morinda citrifolia L.)
title_fullStr Anthraquinone Content in Noni (Morinda citrifolia L.)
title_full_unstemmed Anthraquinone Content in Noni (Morinda citrifolia L.)
title_sort anthraquinone content in noni (morinda citrifolia l.)
publisher Hindawi Limited
series Evidence-Based Complementary and Alternative Medicine
issn 1741-427X
1741-4288
publishDate 2013-01-01
description Noni has been used in traditional medicine and as food for thousands of years. While the fruits serve as food and internal medicine, leaves were traditionally used only topically. In recent years, concern regarding the possible content of anthraquinones in noni has led to scrutiny by the European Food Safety Authority. Little research existed on the content of anthraquinones in different noni preparations, with no information about the potential effect of harvest and preparation methods. Our research focused on lucidin, alizarin, and rubiadin, the most important anthraquinones from a health perspective. We found that the production process (fermentation/juice production versus drying/lyophilization) has no effect on the anthraquinone content. The source product, however, does have implications: noni fruit puree from which seeds had been removed as well as consumer products produced from such puree had no detectable amounts of any anthraquinones. Products that did contain seed or leaf material in all cases did contain partly significant amounts of anthraquinones. To alleviate safety concerns, we suggest that noni products, whether fermented or unfermented juice or powder, should be derived only from fully ripe noni fruits, and that any seed material needs to be removed during the production process.
url http://dx.doi.org/10.1155/2013/208378
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