Relation of Decreased Functional Connectivity Between Left Thalamus and Left Inferior Frontal Gyrus to Emotion Changes Following Acute Sleep Deprivation
Objective: The thalamus is a key node for sleep-wake pathway gate switching during acute sleep deprivation (ASD), and studies have shown that it plays a certain role in emotion changes. However, there are no studies on the association between the thalamus and emotion changes in ASD. In this study, w...
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doaj-bf3af414eb1c4e34b6f8acef990865202021-02-26T06:54:55ZengFrontiers Media S.A.Frontiers in Neurology1664-22952021-02-011210.3389/fneur.2021.642411642411Relation of Decreased Functional Connectivity Between Left Thalamus and Left Inferior Frontal Gyrus to Emotion Changes Following Acute Sleep DeprivationBo-zhi Li0Ya Cao1Ying Zhang2Yang Chen3Yu-hong Gao4Jia-xi Peng5Yong-cong Shao6Xi Zhang7Department of Neurology, Secondary Medical Center, National Clinical Research Center for Geriatric Disease, Chinese PLA General Hospital, Beijing, ChinaDepartment of Neurology, First Medical Center, Chinese PLA General Hospital, Beijing, ChinaDepartment of Medical Psychology, Eighth Medical Center, Chinese PLA General Hospital, Beijing, ChinaSchool of Biological Science and Medical Engineering, Beihang University, Beijing, ChinaDepartment of Neurology, Secondary Medical Center, National Clinical Research Center for Geriatric Disease, Chinese PLA General Hospital, Beijing, ChinaDepartment of Psychology, Beijing Sport University, Beijing, ChinaDepartment of Psychology, Beijing Sport University, Beijing, ChinaDepartment of Neurology, Secondary Medical Center, National Clinical Research Center for Geriatric Disease, Chinese PLA General Hospital, Beijing, ChinaObjective: The thalamus is a key node for sleep-wake pathway gate switching during acute sleep deprivation (ASD), and studies have shown that it plays a certain role in emotion changes. However, there are no studies on the association between the thalamus and emotion changes in ASD. In this study, we used resting-state functional magnetic resonance imaging (R-fMRI) to explore whether changes in the functional connections between the thalamus and other brain regions are related to emotion changes and further explored the function of the thalamus under total ASD conditions.Method: Thirty healthy, right-handed adult men underwent emotional assessment according to the Profile of Mood States Scale and R-fMRI scans before and after ASD. The correlations between changes in functional connectivity between the thalamus and other brain regions and emotion changes were then studied.Results: Positive emotions and psychomotor performance were reduced, and negative emotions were increased following ASD. The functional connections between the left thalamus and left middle temporal gyrus, left inferior frontal gyrus, right thalamus, right inferior temporal gyrus, left middle temporal pole gyrus, right calcarine, left cuneus, left rectus and left medial superior frontal gyrus were significantly altered. Decreased functional connectivity between left thalamus and left inferior frontal gyrus related to emotion changes following ASD.Conclusion: This study finds that functional changes in the thalamus are associated with emotion changes during ASD, suggesting that the left thalamus probably plays an essential role in emotion changes under ASD conditions.https://www.frontiersin.org/articles/10.3389/fneur.2021.642411/fullmoodfunctional connectivityresting-state functional magnetic resonance imagingthalamusinferior frontal gyrusacute sleep deprivation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Bo-zhi Li Ya Cao Ying Zhang Yang Chen Yu-hong Gao Jia-xi Peng Yong-cong Shao Xi Zhang |
spellingShingle |
Bo-zhi Li Ya Cao Ying Zhang Yang Chen Yu-hong Gao Jia-xi Peng Yong-cong Shao Xi Zhang Relation of Decreased Functional Connectivity Between Left Thalamus and Left Inferior Frontal Gyrus to Emotion Changes Following Acute Sleep Deprivation Frontiers in Neurology mood functional connectivity resting-state functional magnetic resonance imaging thalamus inferior frontal gyrus acute sleep deprivation |
author_facet |
Bo-zhi Li Ya Cao Ying Zhang Yang Chen Yu-hong Gao Jia-xi Peng Yong-cong Shao Xi Zhang |
author_sort |
Bo-zhi Li |
title |
Relation of Decreased Functional Connectivity Between Left Thalamus and Left Inferior Frontal Gyrus to Emotion Changes Following Acute Sleep Deprivation |
title_short |
Relation of Decreased Functional Connectivity Between Left Thalamus and Left Inferior Frontal Gyrus to Emotion Changes Following Acute Sleep Deprivation |
title_full |
Relation of Decreased Functional Connectivity Between Left Thalamus and Left Inferior Frontal Gyrus to Emotion Changes Following Acute Sleep Deprivation |
title_fullStr |
Relation of Decreased Functional Connectivity Between Left Thalamus and Left Inferior Frontal Gyrus to Emotion Changes Following Acute Sleep Deprivation |
title_full_unstemmed |
Relation of Decreased Functional Connectivity Between Left Thalamus and Left Inferior Frontal Gyrus to Emotion Changes Following Acute Sleep Deprivation |
title_sort |
relation of decreased functional connectivity between left thalamus and left inferior frontal gyrus to emotion changes following acute sleep deprivation |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Neurology |
issn |
1664-2295 |
publishDate |
2021-02-01 |
description |
Objective: The thalamus is a key node for sleep-wake pathway gate switching during acute sleep deprivation (ASD), and studies have shown that it plays a certain role in emotion changes. However, there are no studies on the association between the thalamus and emotion changes in ASD. In this study, we used resting-state functional magnetic resonance imaging (R-fMRI) to explore whether changes in the functional connections between the thalamus and other brain regions are related to emotion changes and further explored the function of the thalamus under total ASD conditions.Method: Thirty healthy, right-handed adult men underwent emotional assessment according to the Profile of Mood States Scale and R-fMRI scans before and after ASD. The correlations between changes in functional connectivity between the thalamus and other brain regions and emotion changes were then studied.Results: Positive emotions and psychomotor performance were reduced, and negative emotions were increased following ASD. The functional connections between the left thalamus and left middle temporal gyrus, left inferior frontal gyrus, right thalamus, right inferior temporal gyrus, left middle temporal pole gyrus, right calcarine, left cuneus, left rectus and left medial superior frontal gyrus were significantly altered. Decreased functional connectivity between left thalamus and left inferior frontal gyrus related to emotion changes following ASD.Conclusion: This study finds that functional changes in the thalamus are associated with emotion changes during ASD, suggesting that the left thalamus probably plays an essential role in emotion changes under ASD conditions. |
topic |
mood functional connectivity resting-state functional magnetic resonance imaging thalamus inferior frontal gyrus acute sleep deprivation |
url |
https://www.frontiersin.org/articles/10.3389/fneur.2021.642411/full |
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