Functionalization of 3D Polylactic Acid Sponge Using Atmospheric Pressure Cold Plasma
The deposition of organic functionalities on biomaterials to immobilize biomolecules is a research area of great interest in the medical field. The surface functionalization of a 3D porous scaffolds of PDLLA with carboxyl (-COOH) and amino (-NH2) groups by cold plasma treatment at atmospheric pressu...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2019-01-01
|
Series: | International Journal of Polymer Science |
Online Access: | http://dx.doi.org/10.1155/2019/2575987 |
id |
doaj-bf4e52843deb4654a35dc40ca797390d |
---|---|
record_format |
Article |
spelling |
doaj-bf4e52843deb4654a35dc40ca797390d2020-11-25T00:28:38ZengHindawi LimitedInternational Journal of Polymer Science1687-94221687-94302019-01-01201910.1155/2019/25759872575987Functionalization of 3D Polylactic Acid Sponge Using Atmospheric Pressure Cold PlasmaG. Gatti0D. D’Angelo1M. Errahali2M. Biasizzo3L. Marchese4F. Renò5Dipartimento di Scienze e Innovazione Tecnologica, University of Eastern Piedmont, V. Teresa Michel 11, 15121 Alessandria, ItalyPlasma Nano-Tech, Environment Park S.p.A, Via Livorno 60, 10144 Turin, ItalyDipartimento di Scienze e Innovazione Tecnologica, University of Eastern Piedmont, V. Teresa Michel 11, 15121 Alessandria, ItalyChemistry Department I.F.M, University of Turin, Via Pietro Giuria 7, 10125 Turin, ItalyDipartimento di Scienze e Innovazione Tecnologica, University of Eastern Piedmont, V. Teresa Michel 11, 15121 Alessandria, ItalyInnovative Research Laboratory for Wound Healing, Health Sciences Department, University of Eastern Piedmont, Via Solaroli 17, 28100 Novara, ItalyThe deposition of organic functionalities on biomaterials to immobilize biomolecules is a research area of great interest in the medical field. The surface functionalization of a 3D porous scaffolds of PDLLA with carboxyl (-COOH) and amino (-NH2) groups by cold plasma treatment at atmospheric pressure is described in this paper. Two methods of continuous and pulsed plasma deposition were compared to assess the degree of functionalization of the internal porous 3D scaffold. In particular, the pulsed plasma treatment was found to functionalize uniformly not only the sample surface but also inside the open cavities thanks to its permeability and diffusion in the porous 3D scaffold. The species developed in the plasma were studied by optical emission spectroscopy (OES) technique, while the functionalization of the sponges was evaluated by the Diffuse Reflectance Fourier-Transform Infrared Spectroscopy (DR-FTIR) technique using also the adsorption of ammonia (NH3) and deuterated water (D2O) probe molecules. The functional groups were deposited only on the front of the sponge, then the structural characterization of both front and back of the sponge has demonstrated the uniform functionalization of the entire scaffold.http://dx.doi.org/10.1155/2019/2575987 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
G. Gatti D. D’Angelo M. Errahali M. Biasizzo L. Marchese F. Renò |
spellingShingle |
G. Gatti D. D’Angelo M. Errahali M. Biasizzo L. Marchese F. Renò Functionalization of 3D Polylactic Acid Sponge Using Atmospheric Pressure Cold Plasma International Journal of Polymer Science |
author_facet |
G. Gatti D. D’Angelo M. Errahali M. Biasizzo L. Marchese F. Renò |
author_sort |
G. Gatti |
title |
Functionalization of 3D Polylactic Acid Sponge Using Atmospheric Pressure Cold Plasma |
title_short |
Functionalization of 3D Polylactic Acid Sponge Using Atmospheric Pressure Cold Plasma |
title_full |
Functionalization of 3D Polylactic Acid Sponge Using Atmospheric Pressure Cold Plasma |
title_fullStr |
Functionalization of 3D Polylactic Acid Sponge Using Atmospheric Pressure Cold Plasma |
title_full_unstemmed |
Functionalization of 3D Polylactic Acid Sponge Using Atmospheric Pressure Cold Plasma |
title_sort |
functionalization of 3d polylactic acid sponge using atmospheric pressure cold plasma |
publisher |
Hindawi Limited |
series |
International Journal of Polymer Science |
issn |
1687-9422 1687-9430 |
publishDate |
2019-01-01 |
description |
The deposition of organic functionalities on biomaterials to immobilize biomolecules is a research area of great interest in the medical field. The surface functionalization of a 3D porous scaffolds of PDLLA with carboxyl (-COOH) and amino (-NH2) groups by cold plasma treatment at atmospheric pressure is described in this paper. Two methods of continuous and pulsed plasma deposition were compared to assess the degree of functionalization of the internal porous 3D scaffold. In particular, the pulsed plasma treatment was found to functionalize uniformly not only the sample surface but also inside the open cavities thanks to its permeability and diffusion in the porous 3D scaffold. The species developed in the plasma were studied by optical emission spectroscopy (OES) technique, while the functionalization of the sponges was evaluated by the Diffuse Reflectance Fourier-Transform Infrared Spectroscopy (DR-FTIR) technique using also the adsorption of ammonia (NH3) and deuterated water (D2O) probe molecules. The functional groups were deposited only on the front of the sponge, then the structural characterization of both front and back of the sponge has demonstrated the uniform functionalization of the entire scaffold. |
url |
http://dx.doi.org/10.1155/2019/2575987 |
work_keys_str_mv |
AT ggatti functionalizationof3dpolylacticacidspongeusingatmosphericpressurecoldplasma AT ddangelo functionalizationof3dpolylacticacidspongeusingatmosphericpressurecoldplasma AT merrahali functionalizationof3dpolylacticacidspongeusingatmosphericpressurecoldplasma AT mbiasizzo functionalizationof3dpolylacticacidspongeusingatmosphericpressurecoldplasma AT lmarchese functionalizationof3dpolylacticacidspongeusingatmosphericpressurecoldplasma AT freno functionalizationof3dpolylacticacidspongeusingatmosphericpressurecoldplasma |
_version_ |
1725335157239447552 |