Microthrombotic Renal Vascular Lesions Are Associated to Increased Renal Inflammatory Infiltration in Murine Lupus Nephritis

Microthrombotic Renal Vascular Lesions Are Associated to Increased Renal Inflammatory Infiltration in Murine Lupus Nephritis

Background: Vascular microthrombotic lesions in lupus nephritis with or without antiphospholipid antibodies may relate to worse renal outcomes. Whether microthrombotic lesions are a consequence of renal inflammation or independently contribute to renal damage is unclear. Our aim was to investigate t...

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Bibliographic Details
Main Authors: Elena Gonzalo-Gil, Carmen García-Herrero, Oscar Toldos, Alicia Usategui, Gabriel Criado, Sonia Pérez-Yagüe, Domingo F. Barber, Jose L. Pablos, Maria Galindo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Immunology
Subjects:
microthrombosis
inflammation
lupus nephritis
complement
macrophages
platelets
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01948/full

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