Interplay Between Bacteriophages and Restriction-Modification Systems in Enterococci

Interplay Between Bacteriophages and Restriction-Modification Systems in Enterococci

The complete genomes of Enterococcus faecalis bacteriophages were analyzed for tetranucleotide words avoidance. Very similar tetranucleotide composition was found in all tested genomes with strong underrepresentation of palindromic GATC and GGCC words. This avoidance could be explained as a protecti...

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Main Authors: Pristas Peter, Vandzurova Anna, Javorsky Peter
Format: Article
Language:English
Published: Sciendo 2014-06-01
Series:Nova Biotechnologica et Chimica
Subjects:
Enterococcus
bacteriophage
restriction modification systems
palindrome avoidance
Online Access:http://www.degruyter.com/view/j/nbec.2014.13.issue-1/nbec-2014-0002/nbec-2014-0002.xml?format=INT
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spelling doaj-bf5b05163cb042ddbd5f61ee9406b4982020-11-25T01:28:18ZengSciendoNova Biotechnologica et Chimica1338-69052014-06-01131132010.2478/nbec-2014-0002nbec-2014-0002Interplay Between Bacteriophages and Restriction-Modification Systems in EnterococciPristas Peter0Vandzurova Anna1Javorsky Peter2Institute of Animal Physiology, Slovak Academy of Sciences, Soltesovej 4-6, 040 01 Kosice, SlovakiaInstitute of Animal Physiology, Slovak Academy of Sciences, Soltesovej 4-6, 040 01 Kosice, SlovakiaInstitute of Animal Physiology, Slovak Academy of Sciences, Soltesovej 4-6, 040 01 Kosice, SlovakiaThe complete genomes of Enterococcus faecalis bacteriophages were analyzed for tetranucleotide words avoidance. Very similar tetranucleotide composition was found in all tested genomes with strong underrepresentation of palindromic GATC and GGCC words. This avoidance could be explained as a protection mechanism against host restriction-modification systems as a clear correlation was found between avoidance of palindromic words and the specificity of E. faecalis restriction and modification systems. No similar avoidance of tetranucleotide words was observed for non-palindromic words. A weak correlation was observed between avoidance of tetranucleotide palindromes in bacteriophage genomes and the possession of phage encoded DNA methyltransferases confirming the interrelation between bacteriophage genomes composition and restriction and modification systems in enterococcihttp://www.degruyter.com/view/j/nbec.2014.13.issue-1/nbec-2014-0002/nbec-2014-0002.xml?format=INTEnterococcusbacteriophagerestriction modification systemspalindrome avoidance
collection DOAJ
language English
format Article
sources DOAJ
author Pristas Peter
Vandzurova Anna
Javorsky Peter
spellingShingle Pristas Peter
Vandzurova Anna
Javorsky Peter
Interplay Between Bacteriophages and Restriction-Modification Systems in Enterococci
Nova Biotechnologica et Chimica
Enterococcus
bacteriophage
restriction modification systems
palindrome avoidance
author_facet Pristas Peter
Vandzurova Anna
Javorsky Peter
author_sort Pristas Peter
title Interplay Between Bacteriophages and Restriction-Modification Systems in Enterococci
title_short Interplay Between Bacteriophages and Restriction-Modification Systems in Enterococci
title_full Interplay Between Bacteriophages and Restriction-Modification Systems in Enterococci
title_fullStr Interplay Between Bacteriophages and Restriction-Modification Systems in Enterococci
title_full_unstemmed Interplay Between Bacteriophages and Restriction-Modification Systems in Enterococci
title_sort interplay between bacteriophages and restriction-modification systems in enterococci
publisher Sciendo
series Nova Biotechnologica et Chimica
issn 1338-6905
publishDate 2014-06-01
description The complete genomes of Enterococcus faecalis bacteriophages were analyzed for tetranucleotide words avoidance. Very similar tetranucleotide composition was found in all tested genomes with strong underrepresentation of palindromic GATC and GGCC words. This avoidance could be explained as a protection mechanism against host restriction-modification systems as a clear correlation was found between avoidance of palindromic words and the specificity of E. faecalis restriction and modification systems. No similar avoidance of tetranucleotide words was observed for non-palindromic words. A weak correlation was observed between avoidance of tetranucleotide palindromes in bacteriophage genomes and the possession of phage encoded DNA methyltransferases confirming the interrelation between bacteriophage genomes composition and restriction and modification systems in enterococci
topic Enterococcus
bacteriophage
restriction modification systems
palindrome avoidance
url http://www.degruyter.com/view/j/nbec.2014.13.issue-1/nbec-2014-0002/nbec-2014-0002.xml?format=INT
work_keys_str_mv AT pristaspeter interplaybetweenbacteriophagesandrestrictionmodificationsystemsinenterococci
AT vandzurovaanna interplaybetweenbacteriophagesandrestrictionmodificationsystemsinenterococci
AT javorskypeter interplaybetweenbacteriophagesandrestrictionmodificationsystemsinenterococci
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