Interplay Between Bacteriophages and Restriction-Modification Systems in Enterococci
The complete genomes of Enterococcus faecalis bacteriophages were analyzed for tetranucleotide words avoidance. Very similar tetranucleotide composition was found in all tested genomes with strong underrepresentation of palindromic GATC and GGCC words. This avoidance could be explained as a protecti...
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doaj-bf5b05163cb042ddbd5f61ee9406b4982020-11-25T01:28:18ZengSciendoNova Biotechnologica et Chimica1338-69052014-06-01131132010.2478/nbec-2014-0002nbec-2014-0002Interplay Between Bacteriophages and Restriction-Modification Systems in EnterococciPristas Peter0Vandzurova Anna1Javorsky Peter2Institute of Animal Physiology, Slovak Academy of Sciences, Soltesovej 4-6, 040 01 Kosice, SlovakiaInstitute of Animal Physiology, Slovak Academy of Sciences, Soltesovej 4-6, 040 01 Kosice, SlovakiaInstitute of Animal Physiology, Slovak Academy of Sciences, Soltesovej 4-6, 040 01 Kosice, SlovakiaThe complete genomes of Enterococcus faecalis bacteriophages were analyzed for tetranucleotide words avoidance. Very similar tetranucleotide composition was found in all tested genomes with strong underrepresentation of palindromic GATC and GGCC words. This avoidance could be explained as a protection mechanism against host restriction-modification systems as a clear correlation was found between avoidance of palindromic words and the specificity of E. faecalis restriction and modification systems. No similar avoidance of tetranucleotide words was observed for non-palindromic words. A weak correlation was observed between avoidance of tetranucleotide palindromes in bacteriophage genomes and the possession of phage encoded DNA methyltransferases confirming the interrelation between bacteriophage genomes composition and restriction and modification systems in enterococcihttp://www.degruyter.com/view/j/nbec.2014.13.issue-1/nbec-2014-0002/nbec-2014-0002.xml?format=INTEnterococcusbacteriophagerestriction modification systemspalindrome avoidance |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Pristas Peter Vandzurova Anna Javorsky Peter |
spellingShingle |
Pristas Peter Vandzurova Anna Javorsky Peter Interplay Between Bacteriophages and Restriction-Modification Systems in Enterococci Nova Biotechnologica et Chimica Enterococcus bacteriophage restriction modification systems palindrome avoidance |
author_facet |
Pristas Peter Vandzurova Anna Javorsky Peter |
author_sort |
Pristas Peter |
title |
Interplay Between Bacteriophages and Restriction-Modification Systems in Enterococci |
title_short |
Interplay Between Bacteriophages and Restriction-Modification Systems in Enterococci |
title_full |
Interplay Between Bacteriophages and Restriction-Modification Systems in Enterococci |
title_fullStr |
Interplay Between Bacteriophages and Restriction-Modification Systems in Enterococci |
title_full_unstemmed |
Interplay Between Bacteriophages and Restriction-Modification Systems in Enterococci |
title_sort |
interplay between bacteriophages and restriction-modification systems in enterococci |
publisher |
Sciendo |
series |
Nova Biotechnologica et Chimica |
issn |
1338-6905 |
publishDate |
2014-06-01 |
description |
The complete genomes of Enterococcus faecalis bacteriophages were analyzed for tetranucleotide words avoidance. Very similar tetranucleotide composition was found in all tested genomes with strong underrepresentation of palindromic GATC and GGCC words. This avoidance could be explained as a protection mechanism against host restriction-modification systems as a clear correlation was found between avoidance of palindromic words and the specificity of E. faecalis restriction and modification systems. No similar avoidance of tetranucleotide words was observed for non-palindromic words. A weak correlation was observed between avoidance of tetranucleotide palindromes in bacteriophage genomes and the possession of phage encoded DNA methyltransferases confirming the interrelation between bacteriophage genomes composition and restriction and modification systems in enterococci |
topic |
Enterococcus bacteriophage restriction modification systems palindrome avoidance |
url |
http://www.degruyter.com/view/j/nbec.2014.13.issue-1/nbec-2014-0002/nbec-2014-0002.xml?format=INT |
work_keys_str_mv |
AT pristaspeter interplaybetweenbacteriophagesandrestrictionmodificationsystemsinenterococci AT vandzurovaanna interplaybetweenbacteriophagesandrestrictionmodificationsystemsinenterococci AT javorskypeter interplaybetweenbacteriophagesandrestrictionmodificationsystemsinenterococci |
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1725102509019627520 |