Full-length mRNA sequencing uncovers a widespread coupling between transcription initiation and mRNA processing

Full-length mRNA sequencing uncovers a widespread coupling between transcription initiation and mRNA processing

Abstract Background The multifaceted control of gene expression requires tight coordination of regulatory mechanisms at transcriptional and post-transcriptional level. Here, we studied the interdependence of transcription initiation, splicing and polyadenylation events on single mRNA molecules by fu...

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Bibliographic Details
Main Authors: Seyed Yahya Anvar, Guy Allard, Elizabeth Tseng, Gloria M. Sheynkman, Eleonora de Klerk, Martijn Vermaat, Raymund H. Yin, Hans E. Johansson, Yavuz Ariyurek, Johan T. den Dunnen, Stephen W. Turner, Peter A. C. ‘t Hoen
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-018-1418-0

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