Prevalence of naso-pharyngeal Pneumococcal colonization in children between 1 to 5 years old in pre-school educative centers. 2014-2015

• Main Authors: Dunia María Chavez Amaro, María Felicia Casanova González, María Eugenia Toledo Romaní, Nivaldo Linares Pérez, Gilda Toraño Peraza, Martha Montes de Oca Rivero
• Format: Article
• Language: Spanish
• Published: Centro Provincial de Información de Ciencias Médicas. Cienfuegos 2018-06-01
• Series: Medisur
• Subjects: streptococcus pneumoniae; enfermedades nasofaríngeas; vacunas conjugadas
• Online Access: http://medisur.sld.cu/index.php/medisur/article/view/3779

<p><strong>Foundation</strong>: <em>Streptococcus pneumoniae</em> is part of the normal bacterial flora of the nasal and pharingeal mucosa. Naso-pharyngeal colonization precedes the pneumococcal disease and affected individuals are a reservoir at the community level.<br /><strong>Objective</strong>: to determine the prevalence of global naso-pharyngeal colonization and by serotypes of <em>Streptococcus pneumoniae</em> in children of pre-school age before anti pneumoccocal vaccination.<br /><strong>Methods</strong>: a cross descriptive study in the Cienfuegos Municipality, within the period of June 2014 and April 2015. in children aged between 1 and 5 years attending preschool educative centers (N=1 129). Samples of naso-pharyngeal exudates were taken following the set guidelines. The prevalence of colonization was estimated and the most frequent serotypes were identified.<br /><strong>Results</strong>: the global prevalence of naso-pharyngeal colonization was 32,32 %. The most frequent vaccine serotypes were 19F (6,02 %) and 6B (3,99 %); of those related with the vaccine, 6A predominated (5,49 %) and of the not related to the vaccine the most frequently observed was 14B.<strong><br />Conclusion</strong>: naso-pharyngeal colonization in preschool children not vaccinated against pneumoccocus presented a high prevalence at the expense of the serotypes included in the conjugated anti-peumococcal vaccines.</p>