Pla2g12b and Hpn are genes identified by mouse ENU mutagenesis that affect HDL cholesterol.

Pla2g12b and Hpn are genes identified by mouse ENU mutagenesis that affect HDL cholesterol.

Despite considerable progress understanding genes that affect the HDL particle, its function, and cholesterol content, genes identified to date explain only a small percentage of the genetic variation. We used N-ethyl-N-nitrosourea mutagenesis in mice to discover novel genes that affect HDL choleste...

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Bibliographic Details
Main Authors: Aleksandra Aljakna, Seungbum Choi, Holly Savage, Rachael Hageman Blair, Tongjun Gu, Karen L Svenson, Gary A Churchill, Matt Hibbs, Ron Korstanje
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3422231?pdf=render

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