Detoxification of Mycotoxins through Biotransformation

Mycotoxins are toxic fungal secondary metabolites that pose a major threat to the safety of food and feed. Mycotoxins are usually converted into less toxic or non-toxic metabolites through biotransformation that are often made by living organisms as well as the isolated enzymes. The conversions main...

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Bibliographic Details
Main Authors: Peng Li, Ruixue Su, Ruya Yin, Daowan Lai, Mingan Wang, Yang Liu, Ligang Zhou
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/12/2/121
Description
Summary:Mycotoxins are toxic fungal secondary metabolites that pose a major threat to the safety of food and feed. Mycotoxins are usually converted into less toxic or non-toxic metabolites through biotransformation that are often made by living organisms as well as the isolated enzymes. The conversions mainly include hydroxylation, oxidation, hydrogenation, de-epoxidation, methylation, glycosylation and glucuronidation, esterification, hydrolysis, sulfation, demethylation and deamination. Biotransformations of some notorious mycotoxins such as alfatoxins, alternariol, citrinin, fomannoxin, ochratoxins, patulin, trichothecenes and zearalenone analogues are reviewed in detail. The recent development and applications of mycotoxins detoxification through biotransformation are also discussed.
ISSN:2072-6651