Incidence and mortality of multiple myeloma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016
Abstract Background The accurate information about burden of multiple myeloma (MM) at national and provincial level remains unknown in China. Methods Following the general analytical strategy used in GBD 2016, the age-, sex-, and province-specific incidence and mortality in China were analyzed. Tren...
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doaj-bfc191d11baa447583575697484eea092020-12-13T12:02:35ZengBMCJournal of Hematology & Oncology1756-87222019-12-011211710.1186/s13045-019-0807-5Incidence and mortality of multiple myeloma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016Jiangmei Liu0Weiping Liu1Lan Mi2Xinying Zeng3Cai Cai4Jun Ma5Lijun Wang6Union for China Lymphoma Investigators of the Chinese Society of Clinical OncologyUnion for China Leukemia Investigators of the Chinese Society of Clinical OncologyNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and PreventionKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Lymphoma, Peking University Cancer Hospital & InstituteKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Lymphoma, Peking University Cancer Hospital & InstituteNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and PreventionBeijing Institute of Survey and Mapping, Beijing Municipal Key Laboratory of Urban Spatial Information EngineeringHarbin Institute of Hematology & OncologyNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and PreventionAbstract Background The accurate information about burden of multiple myeloma (MM) at national and provincial level remains unknown in China. Methods Following the general analytical strategy used in GBD 2016, the age-, sex-, and province-specific incidence and mortality in China were analyzed. Trends in the incidence and mortality from 2006 to 2016 were evaluated. Results It was estimated that there were 16,500 new cases and 10,300 deaths of multiple myeloma in China in 2016. The age-standardized incidence rates (ASIR) and mortality rates (ASMR) per 100,000 population were 1.03 (95% UI, 0.88–1.17) and 0.67 (95% UI, 0.59–0.77) in 2016. Males had higher incidence and mortality rates than females in all age groups. An upward trend with age in incidence and mortality was observed. Higher incidence and mortality rates clustered in the developed provinces. The incidence of MM in China increased significantly from 2006 to 2016, while the mortality increased from 2006 to 2014, and remained stable from 2014 to 2016. Conclusion The burden of MM showed a heterogeneous pattern in China, which highlighted the need of tailored disease prevention and control strategies in both national and provincial levels.https://doi.org/10.1186/s13045-019-0807-5Multiple myelomaIncidenceMortalityEpidemiology |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jiangmei Liu Weiping Liu Lan Mi Xinying Zeng Cai Cai Jun Ma Lijun Wang Union for China Lymphoma Investigators of the Chinese Society of Clinical Oncology Union for China Leukemia Investigators of the Chinese Society of Clinical Oncology |
spellingShingle |
Jiangmei Liu Weiping Liu Lan Mi Xinying Zeng Cai Cai Jun Ma Lijun Wang Union for China Lymphoma Investigators of the Chinese Society of Clinical Oncology Union for China Leukemia Investigators of the Chinese Society of Clinical Oncology Incidence and mortality of multiple myeloma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016 Journal of Hematology & Oncology Multiple myeloma Incidence Mortality Epidemiology |
author_facet |
Jiangmei Liu Weiping Liu Lan Mi Xinying Zeng Cai Cai Jun Ma Lijun Wang Union for China Lymphoma Investigators of the Chinese Society of Clinical Oncology Union for China Leukemia Investigators of the Chinese Society of Clinical Oncology |
author_sort |
Jiangmei Liu |
title |
Incidence and mortality of multiple myeloma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016 |
title_short |
Incidence and mortality of multiple myeloma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016 |
title_full |
Incidence and mortality of multiple myeloma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016 |
title_fullStr |
Incidence and mortality of multiple myeloma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016 |
title_full_unstemmed |
Incidence and mortality of multiple myeloma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016 |
title_sort |
incidence and mortality of multiple myeloma in china, 2006–2016: an analysis of the global burden of disease study 2016 |
publisher |
BMC |
series |
Journal of Hematology & Oncology |
issn |
1756-8722 |
publishDate |
2019-12-01 |
description |
Abstract Background The accurate information about burden of multiple myeloma (MM) at national and provincial level remains unknown in China. Methods Following the general analytical strategy used in GBD 2016, the age-, sex-, and province-specific incidence and mortality in China were analyzed. Trends in the incidence and mortality from 2006 to 2016 were evaluated. Results It was estimated that there were 16,500 new cases and 10,300 deaths of multiple myeloma in China in 2016. The age-standardized incidence rates (ASIR) and mortality rates (ASMR) per 100,000 population were 1.03 (95% UI, 0.88–1.17) and 0.67 (95% UI, 0.59–0.77) in 2016. Males had higher incidence and mortality rates than females in all age groups. An upward trend with age in incidence and mortality was observed. Higher incidence and mortality rates clustered in the developed provinces. The incidence of MM in China increased significantly from 2006 to 2016, while the mortality increased from 2006 to 2014, and remained stable from 2014 to 2016. Conclusion The burden of MM showed a heterogeneous pattern in China, which highlighted the need of tailored disease prevention and control strategies in both national and provincial levels. |
topic |
Multiple myeloma Incidence Mortality Epidemiology |
url |
https://doi.org/10.1186/s13045-019-0807-5 |
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