The Control of Anthrax Disease: Diagnosis, Vaccination and Investigation

• Main Authors: Rahmat Setya Adji, Lily Natalia
• Format: Article
• Language: English
• Published: Pusat Penelitian dan Pengembangan Peternakan 2006-12-01
• Series: Wartazoa
• Subjects: Anthrax; Bacillus anthracis; zoonotic disease; disease control
• Online Access: http://medpub.litbang.pertanian.go.id/index.php/wartazoa/article/view/841/850
• ISSN: 0216-6461; 2354-6832

Anthrax is a bacterial disease caused by Bacillus anthracis attacking both animal and human (zoonosis) . The disease is normally associated with domestic livestock such as sheep, goats, and cattle, but humans are also infected due to exposure or comsuming infected animals . The control of anthrax in humans and animals involves developing a diagnostic method for B. anthracis detection and confirmation of anthrax, prevention by vaccines, and disease investigation . Rapid and more accurate diagnosis techniques for anthrax should be developed for improving the conventional method used in Indonesia . Vaccines are effective against anthrax . Current anthrax vaccine used in Indonesia is spores vaccine produced from a non-encapsulated, toxigenic. Sterne strain 34F2 of B. anthracis . The use of this vaccine occasionally causes local pain, necroses at the inoculation site, subcutaneous oedema and occasionally death of the animal . Several vaccines have been developed recently such as sub unit vaccine, anthrax vaccine absorbed (AVA), that contains a protective antigen (PA) component of the anthrax toxin as the major protective immunogen and is usually used in humans. In endemic areas of anthrax, outbreaks still routinely occur almost yearly . Monitoring of the epidemiological patterns of the disease has to be carried out by field investigation .