Epoxyeicosatrienoic Acid Analog EET-A Blunts Development of Lupus Nephritis in Mice

Epoxyeicosatrienoic Acid Analog EET-A Blunts Development of Lupus Nephritis in Mice

Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disorder that causes life threatening renal disease and current therapies are limited with serious side-effects. CYP epoxygenase metabolites of arachidonic acid epoxyeicosatrienoic acids (EETs) demonstrate strong anti-inflammato...

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Bibliographic Details
Main Authors: Md. Abdul Hye Khan, Anna Stavniichuk, Mohammad Abdul Sattar, John R. Falck, John D. Imig
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Pharmacology
Subjects:
lupus nephritis
EET analog
inflammation
chemokine
small lipid mediators
mouse
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00512/full

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