ASSOCIATION OF PULSE WAVE VELOCITY AND BODY MASS INDEX IN HEALTHY MEXICAN POPULATION

• Main Authors: Daniela Avila Novoa, M. Cárdenas, E.G. Cardona, D. Cardona, F. Grover, C. Ramos, J. Trujillo
• Format: Article
• Language: English
• Published: Atlantis Press 2018-12-01
• Series: Artery Research
• Online Access: https://www.atlantis-press.com/article/125929978/view

Rational: Cardiovascular diseases represent the main cause of morbidity and mortality throughout the world (1). Arterial stiffness has shown to be an important predictor of cardiovascular events, and pulse wave velocity (PWV) is a marker of subclinical organ damage which can be measured by different methods, one of which is by means of the brachial ankle pulse wave velocity (baPWV) (2–3). On the other hand, obesity affects a large proportion of the population and is classified according to the body mass index (BMI). Increased BMI is associated with hypertension and increased mortality (4). Objective: Analyse the correlation between baPWV and BMI in healthy subjects. Methodology: An analytical cross-sectional study was carried out in healthy age 18–70 year old subjects, who attended the INTEC, (192 women, 189 men). BMI was calculated with the formula Weight (kg) /Height (m)2, baPWV was measured with the VP1000 plus model BP-203RPE III. Correlations were determined with Spearman’s Rho, differences between groups were determined using Anova with post hoc test. Results: A population of 381 subjects was analyzed, a significant correlation was found between baPWV and BMI (r = 0.332, p = 0.001). Dividing patients according to the degree of BMI a significant difference was found in the baPWV between normal weight-overweight groups (10.63 ± 1.68, 11.57 ± 1.9 (p = 0.001), normal weight –class I obesity (10.63 ± 1.68, 12.21 ± 1.73 (p = 0.001) and normal weight –class II (10.63 ± 1.68; 12.27 ± 2.39 (p = 0.007). Conclusion: A direct correlation between baPWV and the body mass index was found. The greater increase of the baPWV was seen between the groups of normal weight and overweight / Class I obesity/ Class II obesity. Subjects with overweight and grade I obesity represent a group with a significant increase in arterial stiffness which should receive special attention in order to decrease the development of cardiovascular disease.