Pressure mediated hypertrophy and mechanical stretch up-regulate expression of the long form of leptin receptor (ob-Rb) in rat cardiac myocytes

Pressure mediated hypertrophy and mechanical stretch up-regulate expression of the long form of leptin receptor (ob-Rb) in rat cardiac myocytes

<p>Abstract</p> <p>Background</p> <p>Hyperleptinemia is known to participate in cardiac hypertrophy and hypertension, but the relationship between pressure overload and leptin is poorly understood. We therefore examined the expression of leptin (ob) and the leptin recep...

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Bibliographic Details
Main Authors: Matsui Hiroki, Yokoyama Tomoyuki, Tanaka Chie, Sunaga Hiroaki, Koitabashi Norimichi, Takizawa Takako, Arai Masashi, Kurabayashi Masahiko
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Cell Biology
Subjects:
Obesity
Cardiac hypertrophy
Pressure overload
Online Access:http://www.biomedcentral.com/1471-2121/13/37

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