A strategy to improve phasing of whole-genome sequenced individuals through integration of familial information from dense genotype panels
Abstract Background Haplotype reconstruction (phasing) is an essential step in many applications, including imputation and genomic selection. The best phasing methods rely on both familial and linkage disequilibrium (LD) information. With whole-genome sequence (WGS) data, relatively small samples of...
Main Authors: | Pierre Faux, Tom Druet |
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Format: | Article |
Language: | deu |
Published: |
BMC
2017-05-01
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Series: | Genetics Selection Evolution |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12711-017-0321-6 |
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