Interferon-α/β and anti-fibroblast growth factor receptor 1 monoclonal antibody suppress hepatic cancer cells in vitro and in vivo.

Interferon-α/β and anti-fibroblast growth factor receptor 1 monoclonal antibody suppress hepatic cancer cells in vitro and in vivo.

BACKGROUND: Hepatocellular carcinoma (HCC) is the most commonly occurring primary liver cancer and ranks as the fifth most frequently occurring cancer, overall, and the third leading cause of cancer deaths, worldwide. At present, effective therapeutic options available for HCC are limited; consequen...

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Main Authors: Shigeru Sasaki, Tadao Ishida, Minoru Toyota, Akinobu Ota, Hiromu Suzuki, Akinori Takaoka, Hiroshi Yasui, Hiroyuki Yamamoto, Hideyasu Takagi, Masahiro Maeda, Tsutomu Seito, Masayuki Tsujisaki, Yasuhisa Shinomura, Kohzoh Imai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3090414?pdf=render

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