The Association of Osteosarcopenia With Functional Disability in Community-Dwelling Mexican Adults 50 and Older

Background: Osteosarcopenia (OS) has recently been described as a predictor of negative outcomes in older adults. However, this alteration in body composition has not been widely studied. In Mexico and Latin America, no information is available on its frequency or associated factors.Objective: To an...

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Main Authors: Miriam T. López-Teros, Oscar Rosas-Carrasco, Sergio Sánchez-García, Lilia Castro-Porras, Armando Luna-López, Marcela Agudelo-Botero
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.674724/full
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spelling doaj-c042fb3f7ab5422f972151082553340f2021-06-07T05:02:30ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2021-06-01810.3389/fmed.2021.674724674724The Association of Osteosarcopenia With Functional Disability in Community-Dwelling Mexican Adults 50 and OlderMiriam T. López-Teros0Miriam T. López-Teros1Oscar Rosas-Carrasco2Sergio Sánchez-García3Lilia Castro-Porras4Armando Luna-López5Marcela Agudelo-Botero6Medical, Dental and Health Sciences Program, National Autonomous University of Mexico, Mexico City, MexicoHealth Department, Iberoamerican University, Mexico City, MexicoHealth Department, Iberoamerican University, Mexico City, MexicoEpidemiological Research Unit and Health Services, Aging Area, XXI Century National Medical Center, Mexican Social Security Institute, Mexico City, MexicoPolitics, Population and Health Research Center, School of Medicine, National Autonomous University of Mexico, Mexico City, MexicoSub-directorate for Biomedical Research, Basic Research Department, National Institute of Geriatrics, Mexico City, MexicoPolitics, Population and Health Research Center, School of Medicine, National Autonomous University of Mexico, Mexico City, MexicoBackground: Osteosarcopenia (OS) has recently been described as a predictor of negative outcomes in older adults. However, this alteration in body composition has not been widely studied. In Mexico and Latin America, no information is available on its frequency or associated factors.Objective: To analyze the association between OS with FD in community-dwelling Mexican adults 50 and older.Design: Cross-sectional secondary data analysis was performed using primary data from a prospective study Frailty, Dynapenia and Sarcopenia Study in Mexican Adults (FraDySMex).Setting and Participants: Eight hundred and twenty-five people were included, 77.1% women, aged 70.3 ± 10.8 years old.Methods: OS was defined as when the person was diagnosed with sarcopenia (SP) plus osteopenia/osteoporosis. The SP diagnosis was evaluated in accordance with the criteria of the European Working Group for the Definition and Diagnosis of Sarcopenia (EWGSOP), and the osteoporosis diagnosis using World Health Organization (WHO) criteria. Muscle mass and bone mass were evaluated using dual-energy X-ray absorptiometry (DXA). FD was evaluated using the basic activities of daily living (BADL) and the instrumental activities of daily living (IADL). Additional sociodemographic and health co-variables were also included, such as sex, age, education, cognitive status, depression, comorbidity, hospitalization, polypharmacy, urinary incontinence, and nutrition variables such as risk of malnutrition and obesity. Associations between OS with FD were evaluated using multiple logistic regression.Results: The prevalence of OS was 8.9% and that of FD was 8.9%. OS was associated with FD [odds ratio (OR): 1.92; CI 95%: 1.11–3.33].Conclusions and Implications: Comprehensive OS assessment could help clinicians identify risk factors early, and thus mitigate the impact on FD in older people.https://www.frontiersin.org/articles/10.3389/fmed.2021.674724/fullsarcopeniaosteosarcopeniafunctional disabilitycommunity-dwellingMexico City
collection DOAJ
language English
format Article
sources DOAJ
author Miriam T. López-Teros
Miriam T. López-Teros
Oscar Rosas-Carrasco
Sergio Sánchez-García
Lilia Castro-Porras
Armando Luna-López
Marcela Agudelo-Botero
spellingShingle Miriam T. López-Teros
Miriam T. López-Teros
Oscar Rosas-Carrasco
Sergio Sánchez-García
Lilia Castro-Porras
Armando Luna-López
Marcela Agudelo-Botero
The Association of Osteosarcopenia With Functional Disability in Community-Dwelling Mexican Adults 50 and Older
Frontiers in Medicine
sarcopenia
osteosarcopenia
functional disability
community-dwelling
Mexico City
author_facet Miriam T. López-Teros
Miriam T. López-Teros
Oscar Rosas-Carrasco
Sergio Sánchez-García
Lilia Castro-Porras
Armando Luna-López
Marcela Agudelo-Botero
author_sort Miriam T. López-Teros
title The Association of Osteosarcopenia With Functional Disability in Community-Dwelling Mexican Adults 50 and Older
title_short The Association of Osteosarcopenia With Functional Disability in Community-Dwelling Mexican Adults 50 and Older
title_full The Association of Osteosarcopenia With Functional Disability in Community-Dwelling Mexican Adults 50 and Older
title_fullStr The Association of Osteosarcopenia With Functional Disability in Community-Dwelling Mexican Adults 50 and Older
title_full_unstemmed The Association of Osteosarcopenia With Functional Disability in Community-Dwelling Mexican Adults 50 and Older
title_sort association of osteosarcopenia with functional disability in community-dwelling mexican adults 50 and older
publisher Frontiers Media S.A.
series Frontiers in Medicine
issn 2296-858X
publishDate 2021-06-01
description Background: Osteosarcopenia (OS) has recently been described as a predictor of negative outcomes in older adults. However, this alteration in body composition has not been widely studied. In Mexico and Latin America, no information is available on its frequency or associated factors.Objective: To analyze the association between OS with FD in community-dwelling Mexican adults 50 and older.Design: Cross-sectional secondary data analysis was performed using primary data from a prospective study Frailty, Dynapenia and Sarcopenia Study in Mexican Adults (FraDySMex).Setting and Participants: Eight hundred and twenty-five people were included, 77.1% women, aged 70.3 ± 10.8 years old.Methods: OS was defined as when the person was diagnosed with sarcopenia (SP) plus osteopenia/osteoporosis. The SP diagnosis was evaluated in accordance with the criteria of the European Working Group for the Definition and Diagnosis of Sarcopenia (EWGSOP), and the osteoporosis diagnosis using World Health Organization (WHO) criteria. Muscle mass and bone mass were evaluated using dual-energy X-ray absorptiometry (DXA). FD was evaluated using the basic activities of daily living (BADL) and the instrumental activities of daily living (IADL). Additional sociodemographic and health co-variables were also included, such as sex, age, education, cognitive status, depression, comorbidity, hospitalization, polypharmacy, urinary incontinence, and nutrition variables such as risk of malnutrition and obesity. Associations between OS with FD were evaluated using multiple logistic regression.Results: The prevalence of OS was 8.9% and that of FD was 8.9%. OS was associated with FD [odds ratio (OR): 1.92; CI 95%: 1.11–3.33].Conclusions and Implications: Comprehensive OS assessment could help clinicians identify risk factors early, and thus mitigate the impact on FD in older people.
topic sarcopenia
osteosarcopenia
functional disability
community-dwelling
Mexico City
url https://www.frontiersin.org/articles/10.3389/fmed.2021.674724/full
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