Ouabain-Induced Gene Expression Changes in Human iPSC-Derived Neuron Culture Expressing Dopamine and cAMP-Regulated Phosphoprotein 32 and GABA Receptors
Cardiotonic steroids (CTS) are specific inhibitors and endogenous ligands of a key enzyme in the CNS—the Na<sup>+</sup>, K<sup>+</sup>-ATPase, which maintains and creates an ion gradient on the plasma membrane of neurons. CTS cause the activation of various signaling cascades...
Main Authors: | Alexander V. Lopachev, Maria A. Lagarkova, Olga S. Lebedeva, Margarita A. Ezhova, Rogneda B. Kazanskaya, Yulia A. Timoshina, Anastasiya V. Khutorova, Evgeny E. Akkuratov, Tatiana N. Fedorova, Raul R. Gainetdinov |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-02-01
|
Series: | Brain Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3425/11/2/203 |
Similar Items
-
Design of a Tumorigenicity Test for Induced Pluripotent Stem Cell (iPSC)-Derived Cell Products
by: Shin Kawamata, et al.
Published: (2015-01-01) -
Generation of corrected-hiPSC (USTCi001-A-1) from epilepsy patient iPSCs using TALEN-mediated editing of the SCN1A gene
by: Huifang Zhao, et al.
Published: (2020-07-01) -
Standards for Deriving Nonhuman Primate-Induced Pluripotent Stem Cells, Neural Stem Cells and Dopaminergic Lineage
by: Guang Yang, et al.
Published: (2018-09-01) -
LIF-activated Jak signaling determines Esrrb expression during late-stage reprogramming
by: Delun Huang, et al.
Published: (2018-01-01) -
IPSC-derived trophoblasts: a novel model for infections at the maternal fetal interface
by: Wang, Jennifer
Published: (2020)