A cross-sectional analysis of the association between sleep duration and osteoporosis risk in adults using 2005–2010 NHANES
Abstract Controversy remains regarding the relationship between bone health and sleep. In the literature, the effect of sleep on bone density in the clinical setting varies depending on the definition of normal sleep duration, sleep quality, selected population, and diagnostic tools for bone density...
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2021-04-01
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doaj-c07d9ab39878480d9b4e9cb6818071de2021-05-02T11:35:59ZengNature Publishing GroupScientific Reports2045-23222021-04-0111111010.1038/s41598-021-88739-xA cross-sectional analysis of the association between sleep duration and osteoporosis risk in adults using 2005–2010 NHANESChia-Lin Lee0Huey-En Tzeng1Wei-Ju Liu2Chun-Hao Tsai3Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General HospitalDepartment of Internal Medicine, School of Medicine, Taipei Medical UniversityDepartment of Medical Research, Taichung Veterans General HospitalDepartment of Orthopedics, China Medical University HospitalAbstract Controversy remains regarding the relationship between bone health and sleep. In the literature, the effect of sleep on bone density in the clinical setting varies depending on the definition of normal sleep duration, sleep quality, selected population, and diagnostic tools for bone density. The aim of this study was to examine the association between bone mineral density (BMD)assessed by dual-energy X-ray absorptiometry and sleep duration/quality in the defined adult population from the National Health and Nutrition Examination Survey (NHANES) (a national household survey) within a 6-year period (2005–2010) and explore age differences. The basic variables, metabolic diseases, and bone density in the femoral neck as determined through dual-energy X-ray absorptiometry, were segregated, and analyzed according to different sleep durations (1–4, 5–6,7–8, and > 9 h/day) and sleep quality using multinomial regression models. A total of 12,793 subjects were analyzed. Our results reveal that women aged > 50 years with sleep duration < 5 h/day had a 7.35 (CI 3.438–15.715) odds of osteoporosis than those in other groups. This analysis is based on a nationally representative sample using survey and inspection data and clarifies the relationship between bone density and the effect of the combination of sleep quality and duration.https://doi.org/10.1038/s41598-021-88739-x |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chia-Lin Lee Huey-En Tzeng Wei-Ju Liu Chun-Hao Tsai |
spellingShingle |
Chia-Lin Lee Huey-En Tzeng Wei-Ju Liu Chun-Hao Tsai A cross-sectional analysis of the association between sleep duration and osteoporosis risk in adults using 2005–2010 NHANES Scientific Reports |
author_facet |
Chia-Lin Lee Huey-En Tzeng Wei-Ju Liu Chun-Hao Tsai |
author_sort |
Chia-Lin Lee |
title |
A cross-sectional analysis of the association between sleep duration and osteoporosis risk in adults using 2005–2010 NHANES |
title_short |
A cross-sectional analysis of the association between sleep duration and osteoporosis risk in adults using 2005–2010 NHANES |
title_full |
A cross-sectional analysis of the association between sleep duration and osteoporosis risk in adults using 2005–2010 NHANES |
title_fullStr |
A cross-sectional analysis of the association between sleep duration and osteoporosis risk in adults using 2005–2010 NHANES |
title_full_unstemmed |
A cross-sectional analysis of the association between sleep duration and osteoporosis risk in adults using 2005–2010 NHANES |
title_sort |
cross-sectional analysis of the association between sleep duration and osteoporosis risk in adults using 2005–2010 nhanes |
publisher |
Nature Publishing Group |
series |
Scientific Reports |
issn |
2045-2322 |
publishDate |
2021-04-01 |
description |
Abstract Controversy remains regarding the relationship between bone health and sleep. In the literature, the effect of sleep on bone density in the clinical setting varies depending on the definition of normal sleep duration, sleep quality, selected population, and diagnostic tools for bone density. The aim of this study was to examine the association between bone mineral density (BMD)assessed by dual-energy X-ray absorptiometry and sleep duration/quality in the defined adult population from the National Health and Nutrition Examination Survey (NHANES) (a national household survey) within a 6-year period (2005–2010) and explore age differences. The basic variables, metabolic diseases, and bone density in the femoral neck as determined through dual-energy X-ray absorptiometry, were segregated, and analyzed according to different sleep durations (1–4, 5–6,7–8, and > 9 h/day) and sleep quality using multinomial regression models. A total of 12,793 subjects were analyzed. Our results reveal that women aged > 50 years with sleep duration < 5 h/day had a 7.35 (CI 3.438–15.715) odds of osteoporosis than those in other groups. This analysis is based on a nationally representative sample using survey and inspection data and clarifies the relationship between bone density and the effect of the combination of sleep quality and duration. |
url |
https://doi.org/10.1038/s41598-021-88739-x |
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