Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism
Endoplasmic reticulum (ER) stress has been proposed to play a role in metabolic diseases. Here, Sasako and colleagues identify stromal cell-derived factor 2 like 1 (Sdf2l1) as a regulator of the ER stress response to feeding in the liver, and suggest that its downregulation may promote diabetes and...
Main Authors: | Takayoshi Sasako, Mitsuru Ohsugi, Naoto Kubota, Shinsuke Itoh, Yukiko Okazaki, Ai Terai, Tetsuya Kubota, Satoshi Yamashita, Kunio Nakatsukasa, Takumi Kamura, Kaito Iwayama, Kumpei Tokuyama, Hiroshi Kiyonari, Yasuhide Furuta, Junji Shibahara, Masashi Fukayama, Kenichiro Enooku, Kazuya Okushin, Takeya Tsutsumi, Ryosuke Tateishi, Kazuyuki Tobe, Hiroshi Asahara, Kazuhiko Koike, Takashi Kadowaki, Kohjiro Ueki |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-02-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-08591-6 |
Similar Items
-
Downregulation of macrophage Irs2 by hyperinsulinemia impairs IL-4-indeuced M2a-subtype macrophage activation in obesity
by: Tetsuya Kubota, et al.
Published: (2018-11-01) -
Exercise in a metabolic chamber - Effects of exercise on 24 h fat oxidation
by: Kaito Iwayama, et al.
Published: (2012-09-01) -
Meal rich in rapeseed oil increases 24-h fat oxidation more than meal rich in palm oil.
by: Katsuhiko Yajima, et al.
Published: (2018-01-01) -
Subcellular Fractionation Analysis of the Extraction of Ubiquitinated Polytopic Membrane Substrate during ER-Associated Degradation.
by: Kunio Nakatsukasa, et al.
Published: (2016-01-01) -
Preparation and culture of bone marrow-derived macrophages from mice for functional analysis
by: Gotaro Toda, et al.
Published: (2021-03-01)