Somatic mutation and clonal expansions in human tissues

Editorial summary Recent sequencing studies on healthy skin and esophagus have found that, as we age, these tissues become colonized by mutant clones of cells carrying driver mutations in traditional cancer genes. This comment summarizes these findings and discusses their possible implications for o...

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Bibliographic Details
Main Author: Inigo Martincorena
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Genome Medicine
Online Access:http://link.springer.com/article/10.1186/s13073-019-0648-4

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