Use of Short-Chain Fatty Acids for the Recovery of the Intestinal Epithelial Barrier Affected by Bacterial Toxins

Use of Short-Chain Fatty Acids for the Recovery of the Intestinal Epithelial Barrier Affected by Bacterial Toxins

Short-chain fatty acids (SCFAs) are carboxylic acids produced as a result of gut microbial anaerobic fermentation. They activate signaling cascades, acting as ligands of G-protein-coupled receptors, such as GPR41, GPR43, and GPR109A, that can modulate the inflammatory response and increase the intes...

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Bibliographic Details
Main Authors: Diliana Pérez-Reytor, Carlos Puebla, Eduardo Karahanian, Katherine García
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Physiology
Subjects:
short-chain fatty acid
bacterial toxins
tight junctions
epithelial barrier
zonula occludens toxins
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.650313/full

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