Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser Ablation
We assessed xurography and laser ablation for the manufacture of passive micromixers arrays to explore the scalability of unconventional manufacture technologies that could be implemented under the restrictions of the Point of Care for developing countries. In this work, we present a novel split-and...
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doaj-c0e1ef1f7e2242fcb87d0fdc0fee57762020-11-24T23:27:20ZengMDPI AGMicromachines2072-666X2017-05-018514410.3390/mi8050144mi8050144Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser AblationJ. Israel Martínez-López0H.A. Betancourt1Erika García-López2Ciro A. Rodriguez3Hector R. Siller4Tecnológico de Monterrey, Eugenio Garza Sada 2501 Sur, 64849 Monterrey, NL, MexicoTecnológico de Monterrey, Eugenio Garza Sada 2501 Sur, 64849 Monterrey, NL, MexicoTecnológico de Monterrey, Eugenio Garza Sada 2501 Sur, 64849 Monterrey, NL, MexicoTecnológico de Monterrey, Eugenio Garza Sada 2501 Sur, 64849 Monterrey, NL, MexicoTecnológico de Monterrey, Eugenio Garza Sada 2501 Sur, 64849 Monterrey, NL, MexicoWe assessed xurography and laser ablation for the manufacture of passive micromixers arrays to explore the scalability of unconventional manufacture technologies that could be implemented under the restrictions of the Point of Care for developing countries. In this work, we present a novel split-and-recombine (SAR) array design adapted for interfacing standardized dispensing (handheld micropipette) and sampling (microplate reader) equipment. The design was patterned and sealed from A4 sized vinyl sheets (polyvinyl chloride), employing low-cost disposable materials. Manufacture was evaluated measuring the dimensional error with stereoscopic and confocal microscopy. The micromixing efficiency was estimated using a machine vision system for passive driven infusion provided by micropippetting samples of dye and water. It was possible to employ rapid fabrication based on xurography to develop a four channel asymmetric split-and-recombine (ASAR) micromixer with mixing efficiencies ranging from 43% to 65%.http://www.mdpi.com/2072-666X/8/5/144micromixingsplit and recombinerapid manufacturexurographylaser ablation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
J. Israel Martínez-López H.A. Betancourt Erika García-López Ciro A. Rodriguez Hector R. Siller |
spellingShingle |
J. Israel Martínez-López H.A. Betancourt Erika García-López Ciro A. Rodriguez Hector R. Siller Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser Ablation Micromachines micromixing split and recombine rapid manufacture xurography laser ablation |
author_facet |
J. Israel Martínez-López H.A. Betancourt Erika García-López Ciro A. Rodriguez Hector R. Siller |
author_sort |
J. Israel Martínez-López |
title |
Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser Ablation |
title_short |
Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser Ablation |
title_full |
Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser Ablation |
title_fullStr |
Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser Ablation |
title_full_unstemmed |
Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser Ablation |
title_sort |
rapid fabrication of disposable micromixing arrays using xurography and laser ablation |
publisher |
MDPI AG |
series |
Micromachines |
issn |
2072-666X |
publishDate |
2017-05-01 |
description |
We assessed xurography and laser ablation for the manufacture of passive micromixers arrays to explore the scalability of unconventional manufacture technologies that could be implemented under the restrictions of the Point of Care for developing countries. In this work, we present a novel split-and-recombine (SAR) array design adapted for interfacing standardized dispensing (handheld micropipette) and sampling (microplate reader) equipment. The design was patterned and sealed from A4 sized vinyl sheets (polyvinyl chloride), employing low-cost disposable materials. Manufacture was evaluated measuring the dimensional error with stereoscopic and confocal microscopy. The micromixing efficiency was estimated using a machine vision system for passive driven infusion provided by micropippetting samples of dye and water. It was possible to employ rapid fabrication based on xurography to develop a four channel asymmetric split-and-recombine (ASAR) micromixer with mixing efficiencies ranging from 43% to 65%. |
topic |
micromixing split and recombine rapid manufacture xurography laser ablation |
url |
http://www.mdpi.com/2072-666X/8/5/144 |
work_keys_str_mv |
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