The Role of the Notch Signal Pathway in Mucosal Cell Metaplasia in Mouse Acute Otitis Media

Abstract Otitis media (OM) is a major cause of morbidity in pediatric and adult patients. This inflammatory condition is characterized by mucous cell hyperplasia that is thought to produce mucins from the middle ear mucosa. We are interested in the role of Notch signalling pathway in this inflammato...

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Bibliographic Details
Main Authors: Xiang Liu, Ning Cong, Xiang Cheng, Rui Ma, Jing Wang, Yi-bo Huang, Meng Zhao, Xin-wei Wang, Fang-Lu Chi, Dong-Dong Ren
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04639-z