Frequency of motor alterations detected through manometry in patients with esophageal symptoms and scleroderma
Background: Scleroderma can present with esophageal involvement causing important morbidity. Aims: To describe the manometric findings and clinical characteristics of patients with scleroderma and esophageal symptoms. Materials and methods: Patients with scleroderma and esophageal symptoms were eval...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2017-04-01
|
Series: | Revista de Gastroenterología de México (English Edition) |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2255534X17300129 |
id |
doaj-c0f9ad2d3b814fe196e7ff3e8ba03c82 |
---|---|
record_format |
Article |
spelling |
doaj-c0f9ad2d3b814fe196e7ff3e8ba03c822020-11-24T23:24:23ZengElsevierRevista de Gastroenterología de México (English Edition)2255-534X2017-04-0182219319510.1016/j.rgmxen.2016.10.003Frequency of motor alterations detected through manometry in patients with esophageal symptoms and sclerodermaN. Pérez y López0G. Lugo-Zamudio1R.E. Barbosa-Cobos2A. Wong-Lam3E. Torres-López4Clinical and Gastrointestinal Motility Laboratory of GERD and functional gastrointestinal disorders, Hospital Juárez de México, SSA, Mexico City, MexicoMedicine Division, Hospital Juárez de México, SSA, Mexico City, MexicoRheumatology Service, Hospital Juárez de México, SSA, Mexico City, MexicoRheumatology Service, Hospital Juárez de México, SSA, Mexico City, MexicoGeneral Surgery Service, Hospital Ángeles Lindavista, Mexico City, MexicoBackground: Scleroderma can present with esophageal involvement causing important morbidity. Aims: To describe the manometric findings and clinical characteristics of patients with scleroderma and esophageal symptoms. Materials and methods: Patients with scleroderma and esophageal symptoms were evaluated through esophageal manometry within the time frame of one year. Descriptive statistics were carried out and the continuous variables were expressed as means and standard deviation. Frequencies were expressed as percentages. Results: The study included 24 female patients with a mean age of 53.5 years and mean disease progression of 7.84 years. The most frequent findings were short and hypotonic lower esophageal sphincter (mean length 1.58 cm and mean tone 9.49 mmHg) and ineffective esophageal motility (mean non-transmitted waves 92.91%, mean effective primary peristalsis 40.05%, and mean amplitude 13.11 mmHg). The most frequent symptom was dysphagia. Conclusions: Scleroderma is associated with lower esophageal sphincter alterations and symptomatic ineffective esophageal motility.http://www.sciencedirect.com/science/article/pii/S2255534X17300129SclerodermaEsophagusLower esophageal sphincterEsophageal manometryPeristalsis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
N. Pérez y López G. Lugo-Zamudio R.E. Barbosa-Cobos A. Wong-Lam E. Torres-López |
spellingShingle |
N. Pérez y López G. Lugo-Zamudio R.E. Barbosa-Cobos A. Wong-Lam E. Torres-López Frequency of motor alterations detected through manometry in patients with esophageal symptoms and scleroderma Revista de Gastroenterología de México (English Edition) Scleroderma Esophagus Lower esophageal sphincter Esophageal manometry Peristalsis |
author_facet |
N. Pérez y López G. Lugo-Zamudio R.E. Barbosa-Cobos A. Wong-Lam E. Torres-López |
author_sort |
N. Pérez y López |
title |
Frequency of motor alterations detected through manometry in patients with esophageal symptoms and scleroderma |
title_short |
Frequency of motor alterations detected through manometry in patients with esophageal symptoms and scleroderma |
title_full |
Frequency of motor alterations detected through manometry in patients with esophageal symptoms and scleroderma |
title_fullStr |
Frequency of motor alterations detected through manometry in patients with esophageal symptoms and scleroderma |
title_full_unstemmed |
Frequency of motor alterations detected through manometry in patients with esophageal symptoms and scleroderma |
title_sort |
frequency of motor alterations detected through manometry in patients with esophageal symptoms and scleroderma |
publisher |
Elsevier |
series |
Revista de Gastroenterología de México (English Edition) |
issn |
2255-534X |
publishDate |
2017-04-01 |
description |
Background: Scleroderma can present with esophageal involvement causing important morbidity.
Aims: To describe the manometric findings and clinical characteristics of patients with scleroderma and esophageal symptoms.
Materials and methods: Patients with scleroderma and esophageal symptoms were evaluated through esophageal manometry within the time frame of one year. Descriptive statistics were carried out and the continuous variables were expressed as means and standard deviation. Frequencies were expressed as percentages.
Results: The study included 24 female patients with a mean age of 53.5 years and mean disease progression of 7.84 years. The most frequent findings were short and hypotonic lower esophageal sphincter (mean length 1.58 cm and mean tone 9.49 mmHg) and ineffective esophageal motility (mean non-transmitted waves 92.91%, mean effective primary peristalsis 40.05%, and mean amplitude 13.11 mmHg). The most frequent symptom was dysphagia.
Conclusions: Scleroderma is associated with lower esophageal sphincter alterations and symptomatic ineffective esophageal motility. |
topic |
Scleroderma Esophagus Lower esophageal sphincter Esophageal manometry Peristalsis |
url |
http://www.sciencedirect.com/science/article/pii/S2255534X17300129 |
work_keys_str_mv |
AT nperezylopez frequencyofmotoralterationsdetectedthroughmanometryinpatientswithesophagealsymptomsandscleroderma AT glugozamudio frequencyofmotoralterationsdetectedthroughmanometryinpatientswithesophagealsymptomsandscleroderma AT rebarbosacobos frequencyofmotoralterationsdetectedthroughmanometryinpatientswithesophagealsymptomsandscleroderma AT awonglam frequencyofmotoralterationsdetectedthroughmanometryinpatientswithesophagealsymptomsandscleroderma AT etorreslopez frequencyofmotoralterationsdetectedthroughmanometryinpatientswithesophagealsymptomsandscleroderma |
_version_ |
1725561018673790976 |