Synthesis of dihydropyrano[4,3-b]pyranes via a multi-component reaction catalyzed by lipase

A green method for the synthesis of dihydropyrano[4,3-b]pyranes via a three-component reaction catalyzed by lipase is reported firstly. Under the optimal conditions, high yields of dihydropyrano[4,3-b]pyranes (80.8–96.8%) could be obtained in this enzymatic reaction. This study not only expands the...

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Bibliographic Details
Main Authors: Xiao Chen, Weian Zhang, Fengjuan Yang, Chao Guo, Ziyuan Zhao, Di Ji, Fan Zhou, Zhi Wang, Rui Zhao, Lei Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Green Chemistry Letters and Reviews
Subjects:
Online Access:http://dx.doi.org/10.1080/17518253.2017.1285442
Description
Summary:A green method for the synthesis of dihydropyrano[4,3-b]pyranes via a three-component reaction catalyzed by lipase is reported firstly. Under the optimal conditions, high yields of dihydropyrano[4,3-b]pyranes (80.8–96.8%) could be obtained in this enzymatic reaction. This study not only expands the application of lipase in organic synthesis, but also provides an alternative efficient method for the synthesis of dihydropyrano[4,3-b]pyranes.
ISSN:1751-8253
1751-7192