Collagen I Induces Preeclampsia-Like Symptoms by Suppressing Proliferation and Invasion of Trophoblasts

Collagen I Induces Preeclampsia-Like Symptoms by Suppressing Proliferation and Invasion of Trophoblasts

Preeclampsia is a common obstetric disorder affecting 2-8% of pregnancy worldwide. Fibrosis is an important histological change occurring in preeclamptic placenta, and might depend on the excess deposition of collagen I. However, the role of fibrotic placenta and collagen I in the pathogenesis of pr...

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Bibliographic Details
Main Authors: Yinglin Feng, Xia Chen, Huiqiao Wang, Xueping Chen, Zixin Lan, Pan Li, Yingshi Cao, Mian Liu, Jin Lv, Yun Chen, Yu Wang, Chao Sheng, Yingying Huang, Mei Zhong, Zhijian Wang, Xiaojing Yue, Liping Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Endocrinology
Subjects:
fibrosis
collagen I
preeclampsia
placenta
pathogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.664766/full

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