Type I diabetes mellitus decreases in vivo macrophage-to-feces reverse cholesterol transport despite increased biliary sterol secretion in mice
Type I diabetes mellitus (T1DM) increases atherosclerotic cardiovascular disease; however, the underlying pathophysiology is still incompletely understood. We investigated whether experimental T1DM impacts HDL-mediated reverse cholesterol transport (RCT). C57BL/6J mice with alloxan-induced T1DM had...
Main Authors: | Jan Freark de Boer, Wijtske Annema, Marijke Schreurs, Jelske N. van der Veen, Markus van der Giet, Niels Nijstad, Folkert Kuipers, Uwe J.F. Tietge |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-03-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520413501 |
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