Exosomal miR-92b-3p Promotes Chemoresistance of Small Cell Lung Cancer Through the PTEN/AKT Pathway

Exosomal miR-92b-3p Promotes Chemoresistance of Small Cell Lung Cancer Through the PTEN/AKT Pathway

Resistance to first-line chemotherapy drugs has become an obstacle to improving the clinical prognosis of patients with small cell lung cancer (SCLC). Exosomal microRNAs have been shown to play pro- and anti-chemoresistant roles in various cancers, but their role in SCLC chemoresistance has never be...

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Bibliographic Details
Main Authors: Ming Li, Wulin Shan, Yan Hua, Fengmei Chao, Yayun Cui, Lei Lv, Xiaoyan Dou, Xing Bian, Jinglu Zou, Hong Li, Wenchu Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
exosome
miR-92b-3p
small cell lung cancer
chemoresistance
migration
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.661602/full

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