Macrophages attenuate the transcription of CYP1A1 in breast tumor cells and enhance their proliferation.
While aberrant cells are routinely recognized and removed by immune cells, tumors eventually escape innate immune responses. Infiltrating immune cells are even corrupted by the tumor to acquire a tumor-supporting phenotype. In line, tumor-associated macrophages are well-characterized to promote tumo...
Main Authors: | Sofia Winslow, Anica Scholz, Peter Rappl, Thilo F Brauß, Christina Mertens, Michaela Jung, Andreas Weigert, Bernhard Brüne, Tobias Schmid |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0209694 |
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