Bifidobacterial Transfer from Mother to Child as Examined by an Animal Model
Bifidobacteria commonly constitute the most abundant group of microorganisms in the healthy infant gut. Their intestinal establishment is believed to be maternally driven, and their acquisition has even been postulated to occur during pregnancy. In the current study, we evaluated bifidobacterial mot...
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MDPI AG
2019-08-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/7/9/293 |
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doaj-c184d822988643358bd22c1fb9b463242020-11-25T01:50:21ZengMDPI AGMicroorganisms2076-26072019-08-017929310.3390/microorganisms7090293microorganisms7090293Bifidobacterial Transfer from Mother to Child as Examined by an Animal ModelWalter Mancino0Sabrina Duranti1Leonardo Mancabelli2Giulia Longhi3Rosaria Anzalone4Christian Milani5Gabriele Andrea Lugli6Luca Carnevali7Rosario Statello8Andrea Sgoifo9Douwe van Sinderen10Marco Ventura11Francesca Turroni12Laboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, ItalyLaboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, ItalyLaboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, ItalyGenProbio srl, 43124 Parma, ItalyGenProbio srl, 43124 Parma, ItalyLaboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, ItalyLaboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, ItalyStress Physiology Laboratory, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, ItalyStress Physiology Laboratory, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, ItalyStress Physiology Laboratory, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, ItalySchool of Microbiology & APC Microbiome Institute, University College Cork, T12 YT20 Cork, IrelandLaboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, ItalyLaboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, ItalyBifidobacteria commonly constitute the most abundant group of microorganisms in the healthy infant gut. Their intestinal establishment is believed to be maternally driven, and their acquisition has even been postulated to occur during pregnancy. In the current study, we evaluated bifidobacterial mother-to infant transmission events in a rat model by means of quantitative PCR (qPCR), as well as by Internally Transcribed Spacer (ITS) bifidobacterial profiling. The occurrence of strains supplied by mothers during pregnancy to their corresponding newborns was observed and identified by analysis immediately following C-section delivery. These findings provide intriguing support for the existence of an unknown route to facilitate bifidobacterial transfer during the very early stages of life.https://www.mdpi.com/2076-2607/7/9/293bifidobacteriainfant gut microbiotamicrobe-host coevolutionmetagenomics |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Walter Mancino Sabrina Duranti Leonardo Mancabelli Giulia Longhi Rosaria Anzalone Christian Milani Gabriele Andrea Lugli Luca Carnevali Rosario Statello Andrea Sgoifo Douwe van Sinderen Marco Ventura Francesca Turroni |
| spellingShingle |
Walter Mancino Sabrina Duranti Leonardo Mancabelli Giulia Longhi Rosaria Anzalone Christian Milani Gabriele Andrea Lugli Luca Carnevali Rosario Statello Andrea Sgoifo Douwe van Sinderen Marco Ventura Francesca Turroni Bifidobacterial Transfer from Mother to Child as Examined by an Animal Model Microorganisms bifidobacteria infant gut microbiota microbe-host coevolution metagenomics |
| author_facet |
Walter Mancino Sabrina Duranti Leonardo Mancabelli Giulia Longhi Rosaria Anzalone Christian Milani Gabriele Andrea Lugli Luca Carnevali Rosario Statello Andrea Sgoifo Douwe van Sinderen Marco Ventura Francesca Turroni |
| author_sort |
Walter Mancino |
| title |
Bifidobacterial Transfer from Mother to Child as Examined by an Animal Model |
| title_short |
Bifidobacterial Transfer from Mother to Child as Examined by an Animal Model |
| title_full |
Bifidobacterial Transfer from Mother to Child as Examined by an Animal Model |
| title_fullStr |
Bifidobacterial Transfer from Mother to Child as Examined by an Animal Model |
| title_full_unstemmed |
Bifidobacterial Transfer from Mother to Child as Examined by an Animal Model |
| title_sort |
bifidobacterial transfer from mother to child as examined by an animal model |
| publisher |
MDPI AG |
| series |
Microorganisms |
| issn |
2076-2607 |
| publishDate |
2019-08-01 |
| description |
Bifidobacteria commonly constitute the most abundant group of microorganisms in the healthy infant gut. Their intestinal establishment is believed to be maternally driven, and their acquisition has even been postulated to occur during pregnancy. In the current study, we evaluated bifidobacterial mother-to infant transmission events in a rat model by means of quantitative PCR (qPCR), as well as by Internally Transcribed Spacer (ITS) bifidobacterial profiling. The occurrence of strains supplied by mothers during pregnancy to their corresponding newborns was observed and identified by analysis immediately following C-section delivery. These findings provide intriguing support for the existence of an unknown route to facilitate bifidobacterial transfer during the very early stages of life. |
| topic |
bifidobacteria infant gut microbiota microbe-host coevolution metagenomics |
| url |
https://www.mdpi.com/2076-2607/7/9/293 |
| work_keys_str_mv |
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