Goodpasture’s syndrome in 17-year-old patient
Goodpasture’s syndrome (GS) is a severe autoimmune disease, which is characterized by kidney and lung affection. Antibodies to glomerular basal membrane (AGBM) are considered to be a specific marker. We present a literature review and a clinical case of GS with typical clinical presentation and low...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Peoples’ Friendship University of Russia (RUDN University)
2016-12-01
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| Series: | RUDN Journal of Medicine |
| Subjects: | |
| Online Access: | http://journals.rudn.ru/medicine/article/view/3756 |
| Summary: | Goodpasture’s syndrome (GS) is a severe autoimmune disease, which is characterized by kidney and lung affection. Antibodies to glomerular basal membrane (AGBM) are considered to be a specific marker. We present a literature review and a clinical case of GS with typical clinical presentation and low effectiveness of glucocorticosteroid treatment in 17-year-old patient. The disease was characterized by the AGBM disappearance from peripheral blood, positive test for cryoglobulins and improvement of patient condition during therapy with rituximab. |
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| ISSN: | 2313-0245 2313-0261 |