Molecular Cloning, Carbohydrate Specificity and the Crystal Structure of Two Sclerotium rolfsii Lectin Variants

Molecular Cloning, Carbohydrate Specificity and the Crystal Structure of Two Sclerotium rolfsii Lectin Variants

SRL is a cell wall associated developmental-stage specific lectin secreted by Sclerotium rolfsii, a soil-born pathogenic fungus. SRL displays specificity for TF antigen (Galβ1→3GalNAc-α-Ser//Thr) expressed in all cancer types and has tumour suppressing effects in vivo. Considering the immense potent...

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Bibliographic Details
Main Authors: Vassiliki I. Peppa, Hemalatha Venkat, Anastassia L. Kantsadi, Shashikala R. Inamdar, Ganapati G. Bhat, Sachin Eligar, Anupama Shivanand, Vishwanath B. Chachadi, Gonchigar J. Satisha, Bale M. Swamy, Vassiliki T. Skamnaki, Spyridon E. Zographos, Demetres D. Leonidas
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Molecules
Subjects:
Sclerotium rolfsii lectin
variant forms
gene constructs
glycan array
carbohydrate binding
X-ray crystallography
Online Access:http://www.mdpi.com/1420-3049/20/6/10848

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http://www.mdpi.com/1420-3049/20/6/10848

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