NH-Polyfluoroalkyl іminophosphonates in the synthesis of α-amino-α-polyfluoroalkyl-γ-oxobutylphosphonic acids

NH-Polyfluoroalkyl іminophosphonates in the synthesis of α-amino-α-polyfluoroalkyl-γ-oxobutylphosphonic acids

Aim. To develop the preparative method for the synthesis of optically active α-amino-α-polyfluoroalkyl-γ-oxobutylphosphonic acids as new promising chiral building blocks. Results and discussion. It has been shown that the reaction of NH-polyfluoroalkyl aminophosphonates with acetone in the presence...

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Bibliographic Details
Main Authors: O. V. Stanko, Y. P. Yelenich, P. P. Onys’ko, Yu. V. Rassukana
Format: Article
Language:English
Published: National University of Pharmacy (Kharkiv, Ukraine) 2019-05-01
Series:Журнал органічної та фармацевтичної хімії
Subjects:
оptically active aminophosphonates
рolyfluoroalkylated aminophosphonic acids
іminophosphonates
stereoselective synthesis
Online Access:http://ophcj.nuph.edu.ua/article/view/ophcj.19.967/170513

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