Dynamic surface activity of a fully synthetic phospholipase-resistant lipid/peptide lung surfactant.

Dynamic surface activity of a fully synthetic phospholipase-resistant lipid/peptide lung surfactant.

This study examines the surface activity and resistance to phospholipase degradation of a fully-synthetic lung surfactant containing a novel diether phosphonolipid (DEPN-8) plus a 34 amino acid peptide (Mini-B) related to native surfactant protein (SP)-B. Activity studies used adsorption, pulsating...

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Bibliographic Details
Main Authors: Frans J Walther, Alan J Waring, Jose M Hernandez-Juviel, Larry M Gordon, Adrian L Schwan, Chun-Ling Jung, Yusuo Chang, Zhengdong Wang, Robert H Notter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2013942?pdf=render

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