Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru

Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru

Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among 3,098 pulmonary TB patients in Lima, Peru. The 161 patients with polyclonal infection were more likely than the 115 with cl...

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Main Authors: Ruvandhi R. Nathavitharana, Cynthia X. Shi, Leonid Chindelevitch, Roger Calderon, Zibiao Zhang, Jerome T. Galea, Carmen Contreras, Rosa Yataco, Leonid Lecca, Mercedes C. Becerra, Megan B. Murray, Ted Cohen
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2017-11-01
Series:Emerging Infectious Diseases
Subjects:
tuberculosis
TB
strain diversity
multidrug-resistant TB
polyclonal infection
Mycobacterium tuberculosis
Online Access:https://wwwnc.cdc.gov/eid/article/23/11/17-0077_article
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spelling doaj-c20eef0b0dbd4135b73e9850b4dac74e2020-11-25T01:49:06ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592017-11-0123111887189010.3201/eid2311.170077Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, PeruRuvandhi R. NathavitharanaCynthia X. ShiLeonid ChindelevitchRoger CalderonZibiao ZhangJerome T. GaleaCarmen ContrerasRosa YatacoLeonid LeccaMercedes C. BecerraMegan B. MurrayTed CohenBecause within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among 3,098 pulmonary TB patients in Lima, Peru. The 161 patients with polyclonal infection were more likely than the 115 with clonal or the 2,822 with simple infections to have multidrug-resistant TB.https://wwwnc.cdc.gov/eid/article/23/11/17-0077_articletuberculosisTBstrain diversitymultidrug-resistant TBpolyclonal infectionMycobacterium tuberculosis
collection DOAJ
language English
format Article
sources DOAJ
author Ruvandhi R. Nathavitharana
Cynthia X. Shi
Leonid Chindelevitch
Roger Calderon
Zibiao Zhang
Jerome T. Galea
Carmen Contreras
Rosa Yataco
Leonid Lecca
Mercedes C. Becerra
Megan B. Murray
Ted Cohen
spellingShingle Ruvandhi R. Nathavitharana
Cynthia X. Shi
Leonid Chindelevitch
Roger Calderon
Zibiao Zhang
Jerome T. Galea
Carmen Contreras
Rosa Yataco
Leonid Lecca
Mercedes C. Becerra
Megan B. Murray
Ted Cohen
Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru
Emerging Infectious Diseases
tuberculosis
TB
strain diversity
multidrug-resistant TB
polyclonal infection
Mycobacterium tuberculosis
author_facet Ruvandhi R. Nathavitharana
Cynthia X. Shi
Leonid Chindelevitch
Roger Calderon
Zibiao Zhang
Jerome T. Galea
Carmen Contreras
Rosa Yataco
Leonid Lecca
Mercedes C. Becerra
Megan B. Murray
Ted Cohen
author_sort Ruvandhi R. Nathavitharana
title Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru
title_short Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru
title_full Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru
title_fullStr Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru
title_full_unstemmed Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru
title_sort polyclonal pulmonary tuberculosis infections and risk for multidrug resistance, lima, peru
publisher Centers for Disease Control and Prevention
series Emerging Infectious Diseases
issn 1080-6040
1080-6059
publishDate 2017-11-01
description Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among 3,098 pulmonary TB patients in Lima, Peru. The 161 patients with polyclonal infection were more likely than the 115 with clonal or the 2,822 with simple infections to have multidrug-resistant TB.
topic tuberculosis
TB
strain diversity
multidrug-resistant TB
polyclonal infection
Mycobacterium tuberculosis
url https://wwwnc.cdc.gov/eid/article/23/11/17-0077_article
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