Efficacy of protein-free calf blood extract ophthalmic gel for children dry eye

• Main Authors: Jun Ouyang, Xiao-Yong Qu, Hong-Feng Li
• Format: Article
• Language: English
• Published: Press of International Journal of Ophthalmology (IJO PRESS) 2014-12-01
• Series: Guoji Yanke Zazhi
• Subjects: protein-free calf blood extract ophthalmic gel; children; dry eye
• Online Access: http://ies.ijo.cn/cn_publish/2014/12/201412054.pdf

AIM: To evaluate the clinic efficacy of protein-free calf blood extract ophthalmic gel on healing children dry eye. <p>METHODS: One hundred patients(50 patients each group)with children dry eye were divided into two groups randomly: control group was dropped 1g/L sodium hyaluronate eye drop four times per day and experimental group was dropped protein-free calf blood extract ophthalmic gel four times per day. Both groups received the depathogeny treatment at the same time. Symptom scores, Schirmer I test values, tear break-up time(BUT), cornea fluorescein staining scores were recorded on the prior treatment and 30d post-treatment, then they were analyzed. <p>RESULTS: There were statistically significant difference(<i>P</i><0.05)for the comparison in the symptom scores, Schirmer I test values, BUT, cornea fluorescein staining scores of prior treatment and post-treatment in each groups. And there were statistically significant difference(<i>P</i><0.05)in the same items of post-treatment between the two groups. <p>CONCLUSION: There is a clearly beneficial effect of protein-free calf blood extract ophthalmic gel on healing children dry eye.