B cell depletion in HIV-1 subtype A infected Ugandan adults: relationship to CD4 T cell count, viral load and humoral immune responses.

B cell depletion in HIV-1 subtype A infected Ugandan adults: relationship to CD4 T cell count, viral load and humoral immune responses.

To better understand the nature of B cell dysfunctions in subjects infected with HIV-1 subtype A, a rural cohort of 50 treatment-naïve Ugandan patients chronically infected with HIV-1 subtype A was studied, and the relationship between B cell depletion and HIV disease was assessed. B cell absolute c...

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Bibliographic Details
Main Authors: Peter Oballah, Britta Flach, Leigh A Eller, Michael A Eller, Benson Ouma, Mark de Souza, Hannah N Kibuuka, Fred Wabwire-Mangen, Bruce K Brown, Nelson L Michael, Merlin L Robb, David Montefiori, Victoria R Polonis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3160298?pdf=render

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