Changes in Infant and Neonatal Mortality and Associated Factors in Eight Cohorts from Three Brazilian Cities
Abstract Stillbirth (SBR), perinatal (PMR), neonatal (NMR) and infant mortality rates (IMR) are declining in Brazil and the factors associated with these falls are still being investigated. The objective of the present study was to assess changes in SBR, PMR, NMR and IMR over time and to determine t...
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doaj-c224367cd4594817912b21569fd52c562021-02-23T09:31:02ZengNature Publishing GroupScientific Reports2045-23222020-02-011011810.1038/s41598-020-59910-7Changes in Infant and Neonatal Mortality and Associated Factors in Eight Cohorts from Three Brazilian CitiesCarolina A. Carvalho0Antônio A. M. da Silva1César Victora2Marcelo Goldani3Heloísa Bettiol4Erika Barbara Abreu Fonseca Thomaz5Fernando Barros6Bernardo L. Horta7Ana Menezes8Viviane Cardoso9Ricardo Carvalho Cavalli10Iná Santos11Rosângela F. L. Batista12Vanda Maria Simões13Marco Barbieri14Aluisio Barros15Federal Institute of Maranhão; Federal University of Maranhão, Post Graduate Program in Collective Health, Rua Barão de Itapary, nº 155, CentroFederal University of Maranhão, Post Graduate Program in Collective Health, Rua Barão de Itapary, nº 155, CentroFederal University of Pelotas, Post Graduate Program in EpidemiologyFederal University of Rio Grande do Sul, Department of PediatricsUniversity of São Paulo, Department of Puericulture and PediatricsFederal University of Maranhão, Post Graduate Program in Collective Health, Rua Barão de Itapary, nº 155, CentroCatholic University of Pelotas, Post-Graduate Program in Health and Behavior and Federal University of Pelotas, Post Graduate Program in EpidemiologyFederal University of Pelotas, Post Graduate Program in EpidemiologyFederal University of Pelotas, Post Graduate Program in EpidemiologyUniversity of São Paulo, Department of Puericulture and PediatricsUniversity of São Paulo, Department of Gynecology and ObstetricsFederal University of Pelotas, Post Graduate Program in EpidemiologyFederal University of Maranhão, Post Graduate Program in Collective Health, Rua Barão de Itapary, nº 155, CentroFederal University of Maranhão, Post Graduate Program in Collective Health, Rua Barão de Itapary, nº 155, CentroUniversity of São Paulo, Department of Puericulture and PediatricsFederal University of Pelotas, Post Graduate Program in EpidemiologyAbstract Stillbirth (SBR), perinatal (PMR), neonatal (NMR) and infant mortality rates (IMR) are declining in Brazil and the factors associated with these falls are still being investigated. The objective of the present study was to assess changes in SBR, PMR, NMR and IMR over time and to determine the factors associated with changes in NMR and IMR in eight Brazilian cohorts. All cohorts are population-based (Ribeirão Preto in 1978/79, 1994 and 2010; Pelotas in 1982, 1993 and 2004; and São Luís in 1997/98 and 2010). Were included data on 41440 children. All indicators were decreased, except in the city of Pelotas, from 1993 to 2004, and except SBR in São Luís. Sociodemographic variables seem to be able to explain reductions of NMR and IMR in Ribeirão Preto, from 1978/79 to 1994, and in São Luís. In Ribeirão Preto, from 1994 to 2010 declines in NMR and IMR seem to be explained by reductions in intrauterine growth restriction (IUGR). Newborn’s gestational age had diminished in all cohorts, preventing even greater reductions of NMR and IMR. Improved sociodemographic variables and reduction of IUGR, seem to be able to explain part of the decrease observed. NMR and IMR could have been reduced even more, were it not for the worsening in gestational age distribution.https://doi.org/10.1038/s41598-020-59910-7 |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Carolina A. Carvalho Antônio A. M. da Silva César Victora Marcelo Goldani Heloísa Bettiol Erika Barbara Abreu Fonseca Thomaz Fernando Barros Bernardo L. Horta Ana Menezes Viviane Cardoso Ricardo Carvalho Cavalli Iná Santos Rosângela F. L. Batista Vanda Maria Simões Marco Barbieri Aluisio Barros |
spellingShingle |
Carolina A. Carvalho Antônio A. M. da Silva César Victora Marcelo Goldani Heloísa Bettiol Erika Barbara Abreu Fonseca Thomaz Fernando Barros Bernardo L. Horta Ana Menezes Viviane Cardoso Ricardo Carvalho Cavalli Iná Santos Rosângela F. L. Batista Vanda Maria Simões Marco Barbieri Aluisio Barros Changes in Infant and Neonatal Mortality and Associated Factors in Eight Cohorts from Three Brazilian Cities Scientific Reports |
author_facet |
Carolina A. Carvalho Antônio A. M. da Silva César Victora Marcelo Goldani Heloísa Bettiol Erika Barbara Abreu Fonseca Thomaz Fernando Barros Bernardo L. Horta Ana Menezes Viviane Cardoso Ricardo Carvalho Cavalli Iná Santos Rosângela F. L. Batista Vanda Maria Simões Marco Barbieri Aluisio Barros |
author_sort |
Carolina A. Carvalho |
title |
Changes in Infant and Neonatal Mortality and Associated Factors in Eight Cohorts from Three Brazilian Cities |
title_short |
Changes in Infant and Neonatal Mortality and Associated Factors in Eight Cohorts from Three Brazilian Cities |
title_full |
Changes in Infant and Neonatal Mortality and Associated Factors in Eight Cohorts from Three Brazilian Cities |
title_fullStr |
Changes in Infant and Neonatal Mortality and Associated Factors in Eight Cohorts from Three Brazilian Cities |
title_full_unstemmed |
Changes in Infant and Neonatal Mortality and Associated Factors in Eight Cohorts from Three Brazilian Cities |
title_sort |
changes in infant and neonatal mortality and associated factors in eight cohorts from three brazilian cities |
publisher |
Nature Publishing Group |
series |
Scientific Reports |
issn |
2045-2322 |
publishDate |
2020-02-01 |
description |
Abstract Stillbirth (SBR), perinatal (PMR), neonatal (NMR) and infant mortality rates (IMR) are declining in Brazil and the factors associated with these falls are still being investigated. The objective of the present study was to assess changes in SBR, PMR, NMR and IMR over time and to determine the factors associated with changes in NMR and IMR in eight Brazilian cohorts. All cohorts are population-based (Ribeirão Preto in 1978/79, 1994 and 2010; Pelotas in 1982, 1993 and 2004; and São Luís in 1997/98 and 2010). Were included data on 41440 children. All indicators were decreased, except in the city of Pelotas, from 1993 to 2004, and except SBR in São Luís. Sociodemographic variables seem to be able to explain reductions of NMR and IMR in Ribeirão Preto, from 1978/79 to 1994, and in São Luís. In Ribeirão Preto, from 1994 to 2010 declines in NMR and IMR seem to be explained by reductions in intrauterine growth restriction (IUGR). Newborn’s gestational age had diminished in all cohorts, preventing even greater reductions of NMR and IMR. Improved sociodemographic variables and reduction of IUGR, seem to be able to explain part of the decrease observed. NMR and IMR could have been reduced even more, were it not for the worsening in gestational age distribution. |
url |
https://doi.org/10.1038/s41598-020-59910-7 |
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