Beyond Antimicrobial Resistance: Evidence for a Distinct Role of the AcrD Efflux Pump in Salmonella Biology
For over 20 years, bacterial multidrug resistance (MDR) efflux pumps have been studied because of their impact on resistance to antimicrobials. However, critical questions remain, including why produce efflux pumps under non-antimicrobial treatment conditions, and why have multiple pumps if their on...
Main Authors: | Michelle M. C. Buckner, Jessica M. A. Blair, Roberto M. La Ragione, Jane Newcombe, Daniel J. Dwyer, Alasdair Ivens, Laura J. V. Piddock |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2016-11-01
|
Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/7/6/e01916-16 |
Similar Items
-
AcrB, AcrD, and MdtABC multidrug efflux systems are involved in enterobactin export in Escherichia coli.
by: Tsukasa Horiyama, et al.
Published: (2014-01-01) -
Lack of AcrB Efflux Function Confers Loss of Virulence on Salmonella enterica Serovar Typhimurium
by: Xuan Wang-Kan, et al.
Published: (2017-07-01) -
Chlorpromazine and Amitriptyline Are Substrates and Inhibitors of the AcrB Multidrug Efflux Pump
by: Elizabeth M. Grimsey, et al.
Published: (2020-06-01) -
How to Measure Export via Bacterial Multidrug Resistance Efflux Pumps
by: Jessica M. A. Blair, et al.
Published: (2016-07-01) -
Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB
by: Eamonn Reading, et al.
Published: (2020-11-01)