Selenium in Bone Health: Roles in Antioxidant Protection and Cell Proliferation

Selenium (Se) is an essential trace element for humans and animals, and several findings suggest that dietary Se intake may be necessary for bone health. Such findings may relate to roles of Se in antioxidant protection, enhanced immune surveillance and modulation of cell proliferation. Elucidation...

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Bibliographic Details
Main Authors: Huawei Zeng, Jay J. Cao, Gerald F. Combs
Format: Article
Language:English
Published: MDPI AG 2013-01-01
Series:Nutrients
Subjects:
Online Access:http://www.mdpi.com/2072-6643/5/1/97
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spelling doaj-c23b7bd298024db8961a8ec75bdd0a462020-11-24T20:55:01ZengMDPI AGNutrients2072-66432013-01-01519711010.3390/nu5010097Selenium in Bone Health: Roles in Antioxidant Protection and Cell ProliferationHuawei ZengJay J. CaoGerald F. CombsSelenium (Se) is an essential trace element for humans and animals, and several findings suggest that dietary Se intake may be necessary for bone health. Such findings may relate to roles of Se in antioxidant protection, enhanced immune surveillance and modulation of cell proliferation. Elucidation of the mechanisms by which Se supports these cellular processes can lead to a better understanding of the role of this nutrient in normal bone metabolism. This article reviews the current knowledge concerning the molecular functions of Se relevant to bone health.http://www.mdpi.com/2072-6643/5/1/97antioxidantbone healthcell proliferation
collection DOAJ
language English
format Article
sources DOAJ
author Huawei Zeng
Jay J. Cao
Gerald F. Combs
spellingShingle Huawei Zeng
Jay J. Cao
Gerald F. Combs
Selenium in Bone Health: Roles in Antioxidant Protection and Cell Proliferation
Nutrients
antioxidant
bone health
cell proliferation
author_facet Huawei Zeng
Jay J. Cao
Gerald F. Combs
author_sort Huawei Zeng
title Selenium in Bone Health: Roles in Antioxidant Protection and Cell Proliferation
title_short Selenium in Bone Health: Roles in Antioxidant Protection and Cell Proliferation
title_full Selenium in Bone Health: Roles in Antioxidant Protection and Cell Proliferation
title_fullStr Selenium in Bone Health: Roles in Antioxidant Protection and Cell Proliferation
title_full_unstemmed Selenium in Bone Health: Roles in Antioxidant Protection and Cell Proliferation
title_sort selenium in bone health: roles in antioxidant protection and cell proliferation
publisher MDPI AG
series Nutrients
issn 2072-6643
publishDate 2013-01-01
description Selenium (Se) is an essential trace element for humans and animals, and several findings suggest that dietary Se intake may be necessary for bone health. Such findings may relate to roles of Se in antioxidant protection, enhanced immune surveillance and modulation of cell proliferation. Elucidation of the mechanisms by which Se supports these cellular processes can lead to a better understanding of the role of this nutrient in normal bone metabolism. This article reviews the current knowledge concerning the molecular functions of Se relevant to bone health.
topic antioxidant
bone health
cell proliferation
url http://www.mdpi.com/2072-6643/5/1/97
work_keys_str_mv AT huaweizeng seleniuminbonehealthrolesinantioxidantprotectionandcellproliferation
AT jayjcao seleniuminbonehealthrolesinantioxidantprotectionandcellproliferation
AT geraldfcombs seleniuminbonehealthrolesinantioxidantprotectionandcellproliferation
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