Detecting identity by descent and homozygosity mapping in whole-exome sequencing data.

Detecting identity by descent and homozygosity mapping in whole-exome sequencing data.

The detection of genetic segments of Identical by Descent (IBD) in Genome-Wide Association Studies has proven successful in pinpointing genetic relatedness between reportedly unrelated individuals and leveraging such regions to shortlist candidate genes. These techniques depend on high-density genot...

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Bibliographic Details
Main Authors:	Zhong Zhuang, Alexander Gusev, Judy Cho, Itsik Pe'er
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3469503?pdf=render

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