Insights into Nuclear G-Protein-Coupled Receptors as Therapeutic Targets in Non-Communicable Diseases

Insights into Nuclear G-Protein-Coupled Receptors as Therapeutic Targets in Non-Communicable Diseases

G-protein-coupled receptors (GPCRs) comprise a large protein superfamily divided into six classes, rhodopsin-like (A), secretin receptor family (B), metabotropic glutamate (C), fungal mating pheromone receptors (D), cyclic AMP receptors (E) and frizzled (F). Until recently, GPCRs signaling was thoug...

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Bibliographic Details
Main Authors: Salomé Gonçalves-Monteiro, Rita Ribeiro-Oliveira, Maria Sofia Vieira-Rocha, Martin Vojtek, Joana B. Sousa, Carmen Diniz
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceuticals
Subjects:
GPCRs
cancer
cardiovascular diseases
ligands
nuclear GPCR signaling
GPCR-based therapeutics
Online Access:https://www.mdpi.com/1424-8247/14/5/439

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