Silencing of PGK1 Promotes Sensitivity to Paclitaxel Treatment by Upregulating XAF1-Mediated Apoptosis in Triple-Negative Breast Cancer
Objective: Triple negative breast cancer (TNBC) is known to have aggressive clinical course and a high risk of recurrence. Given the lack of effective targeted therapy options, paclitaxel-based chemotherapy is still the primary option for TNBC patients. However, patients who fail to achieve a comple...
Main Authors: | Shanshan Sun, Hao Wu, Xiaohong Wu, Zilong You, Yang Jiang, Xiaoshuan Liang, Zhuo Chen, Ye Zhang, Wei Wei, Yongdong Jiang, Yanbo Chen, Yanni Song, Da Pang |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-03-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2021.535230/full |
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