Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank

Here, Richa Saxena and colleagues perform a genome-wide association study (GWAS) of self-reported morningness/eveningness preference in the UKBiobank cohort, and identify new genetic loci that contribute to a person's chronotype.

Bibliographic Details
Main Authors: Jacqueline M. Lane, Irma Vlasac, Simon G. Anderson, Simon D. Kyle, William G. Dixon, David A. Bechtold, Shubhroz Gill, Max A. Little, Annemarie Luik, Andrew Loudon, Richard Emsley, Frank A. J. L. Scheer, Deborah A. Lawlor, Susan Redline, David W. Ray, Martin K. Rutter, Richa Saxena
Format: Article
Language:English
Published: Nature Publishing Group 2016-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10889
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spelling doaj-c25bbc1d847e4c298d251095a613c6b12021-05-11T10:37:03ZengNature Publishing GroupNature Communications2041-17232016-03-017111010.1038/ncomms10889Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK BiobankJacqueline M. Lane0Irma Vlasac1Simon G. Anderson2Simon D. Kyle3William G. Dixon4David A. Bechtold5Shubhroz Gill6Max A. Little7Annemarie Luik8Andrew Loudon9Richard Emsley10Frank A. J. L. Scheer11Deborah A. Lawlor12Susan Redline13David W. Ray14Martin K. Rutter15Richa Saxena16Center for Human Genetic Research Massachusetts General HospitalCenter for Human Genetic Research Massachusetts General HospitalCardiovascular Research Group, Institute of Cardiovascular Sciences, The University of ManchesterNuffield Department of Clinical Neurosciences, Sleep and Circadian Neuroscience Institute (SCNi), University of OxfordCentre for Musculoskeletal Research Institute of Inflammation and Repair, The University of ManchesterFaculty of Life Sciences, The University of ManchesterChemical Biology Program, Broad Institute, CambridgeDepartment of Mathematics, Engineering and Applied Science, Aston UniversityNuffield Department of Clinical Neurosciences, Sleep and Circadian Neuroscience Institute (SCNi), University of OxfordFaculty of Life Sciences, The University of ManchesterInstitute of Population Health, The University of ManchesterDivision of Sleep and Circadian Disorders, Brigham and Women’s HospitalMRC Integrative Epidemiology Unit at the University of BristolDivision of Sleep and Circadian Disorders, Brigham and Women’s HospitalCentre for Endocrinology and Diabetes, Institute of Human Development, The University of ManchesterCentre for Endocrinology and Diabetes, Institute of Human Development, The University of ManchesterCenter for Human Genetic Research Massachusetts General HospitalHere, Richa Saxena and colleagues perform a genome-wide association study (GWAS) of self-reported morningness/eveningness preference in the UKBiobank cohort, and identify new genetic loci that contribute to a person's chronotype.https://doi.org/10.1038/ncomms10889
collection DOAJ
language English
format Article
sources DOAJ
author Jacqueline M. Lane
Irma Vlasac
Simon G. Anderson
Simon D. Kyle
William G. Dixon
David A. Bechtold
Shubhroz Gill
Max A. Little
Annemarie Luik
Andrew Loudon
Richard Emsley
Frank A. J. L. Scheer
Deborah A. Lawlor
Susan Redline
David W. Ray
Martin K. Rutter
Richa Saxena
spellingShingle Jacqueline M. Lane
Irma Vlasac
Simon G. Anderson
Simon D. Kyle
William G. Dixon
David A. Bechtold
Shubhroz Gill
Max A. Little
Annemarie Luik
Andrew Loudon
Richard Emsley
Frank A. J. L. Scheer
Deborah A. Lawlor
Susan Redline
David W. Ray
Martin K. Rutter
Richa Saxena
Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank
Nature Communications
author_facet Jacqueline M. Lane
Irma Vlasac
Simon G. Anderson
Simon D. Kyle
William G. Dixon
David A. Bechtold
Shubhroz Gill
Max A. Little
Annemarie Luik
Andrew Loudon
Richard Emsley
Frank A. J. L. Scheer
Deborah A. Lawlor
Susan Redline
David W. Ray
Martin K. Rutter
Richa Saxena
author_sort Jacqueline M. Lane
title Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank
title_short Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank
title_full Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank
title_fullStr Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank
title_full_unstemmed Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank
title_sort genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the uk biobank
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2016-03-01
description Here, Richa Saxena and colleagues perform a genome-wide association study (GWAS) of self-reported morningness/eveningness preference in the UKBiobank cohort, and identify new genetic loci that contribute to a person's chronotype.
url https://doi.org/10.1038/ncomms10889
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