The maternal ITPK1 gene polymorphism is associated with neural tube defects in a high-risk Chinese population.
BACKGROUND: Epidemiological surveys and animal studies have revealed that inositol metabolism is associated with NTDs, but the mechanisms are not clear. Inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) is a pivotal regulatory enzyme in inositol metabolic pathway. The objective was to assess the poten...
Main Authors: | Zhen Guan, Jianhua Wang, Jin Guo, Fang Wang, Xiuwei Wang, Guannan Li, Qiu Xie, Xu Han, Bo Niu, Ting Zhang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3896452?pdf=render |
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