Non-enzymatic decomposition of collagen fibers by a biglycan antibody and a plausible mechanism for rheumatoid arthritis.
Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory and destructive joint disorder that affects tens of millions of people worldwide. Normal healthy joints maintain a balance between the synthesis of extracellular matrix (ECM) molecules and the proteolytic degradation of damaged ones. In...
Main Authors: | Olga Antipova, Joseph P R O Orgel |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3302792?pdf=render |
Similar Items
-
Measurement of Elastic Modulus of Collagen Type I Single Fiber.
by: Pavel Dutov, et al.
Published: (2016-01-01) -
Altered expression of small leucine-rich proteoglycans (Decorin, Biglycan and Lumican): Plausible diagnostic marker in urothelial carcinoma of bladder
by: Sandeep Appunni, et al.
Published: (2017-04-01) -
Collagen Autoantibodies and Their Relationship to CCP Antibodies and Rheumatoid Factor in the Progression of Early Rheumatoid Arthritis
by: Senga F. Whittingham, et al.
Published: (2017-04-01) -
Variation in the helical structure of native collagen.
by: Joseph P R O Orgel, et al.
Published: (2014-01-01) -
Citrullination as a plausible link to periodontitis, rheumatoid arthritis, atherosclerosis and Alzheimer’s disease
by: Ingar Olsen, et al.
Published: (2018-01-01)