Anti-Inflammatory and Anti-Oxidative Activities of Phenolic Compounds from Alnus sibirica Stems Fermented by Lactobacillus plantarum subsp. argentoratensis

Fermentation of Alnus sibirica (AS) stems using Lactobacillus plantarum subsp. argentoratensis was conducted and three compounds isolated from the Alnus species were identified for the first time, 7-(3,4-dihydroxyphenyl)-1-(4-hydroxyphenyl)-heptan-3-one, 1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)-h...

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Main Authors: Thi Tam Le, Jun Yin, MinWon Lee
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/22/9/1566
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spelling doaj-c287fb0d5284459b9685bd27322c7f632020-11-24T21:10:34ZengMDPI AGMolecules1420-30492017-09-01229156610.3390/molecules22091566molecules22091566Anti-Inflammatory and Anti-Oxidative Activities of Phenolic Compounds from Alnus sibirica Stems Fermented by Lactobacillus plantarum subsp. argentoratensisThi Tam Le0Jun Yin1MinWon Lee2Laboratory of Pharmacognosy and Natural Product based Medicine, College of Pharmacy, Chung-Ang University, Seoul 156-756, KoreaLaboratory of Pharmacognosy and Natural Product based Medicine, College of Pharmacy, Chung-Ang University, Seoul 156-756, KoreaLaboratory of Pharmacognosy and Natural Product based Medicine, College of Pharmacy, Chung-Ang University, Seoul 156-756, KoreaFermentation of Alnus sibirica (AS) stems using Lactobacillus plantarum subsp. argentoratensis was conducted and three compounds isolated from the Alnus species were identified for the first time, 7-(3,4-dihydroxyphenyl)-1-(4-hydroxyphenyl)-heptan-3-one, 1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)-heptan-3-one and 4-(3,4-dihydroxyphenyl)-butan-2-one, along with 14 known compounds. The anti-oxidative and anti-inflammatory abilities of AS and fermented AS (FAS) as well as the isolated phenolic compounds from FAS were investigated. FAS showed stronger anti-oxidative and anti-inflammatory activities than non-fermented AS.https://www.mdpi.com/1420-3049/22/9/1566Alnus sibiricafermentationdiarylheptanoid
collection DOAJ
language English
format Article
sources DOAJ
author Thi Tam Le
Jun Yin
MinWon Lee
spellingShingle Thi Tam Le
Jun Yin
MinWon Lee
Anti-Inflammatory and Anti-Oxidative Activities of Phenolic Compounds from Alnus sibirica Stems Fermented by Lactobacillus plantarum subsp. argentoratensis
Molecules
Alnus sibirica
fermentation
diarylheptanoid
author_facet Thi Tam Le
Jun Yin
MinWon Lee
author_sort Thi Tam Le
title Anti-Inflammatory and Anti-Oxidative Activities of Phenolic Compounds from Alnus sibirica Stems Fermented by Lactobacillus plantarum subsp. argentoratensis
title_short Anti-Inflammatory and Anti-Oxidative Activities of Phenolic Compounds from Alnus sibirica Stems Fermented by Lactobacillus plantarum subsp. argentoratensis
title_full Anti-Inflammatory and Anti-Oxidative Activities of Phenolic Compounds from Alnus sibirica Stems Fermented by Lactobacillus plantarum subsp. argentoratensis
title_fullStr Anti-Inflammatory and Anti-Oxidative Activities of Phenolic Compounds from Alnus sibirica Stems Fermented by Lactobacillus plantarum subsp. argentoratensis
title_full_unstemmed Anti-Inflammatory and Anti-Oxidative Activities of Phenolic Compounds from Alnus sibirica Stems Fermented by Lactobacillus plantarum subsp. argentoratensis
title_sort anti-inflammatory and anti-oxidative activities of phenolic compounds from alnus sibirica stems fermented by lactobacillus plantarum subsp. argentoratensis
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2017-09-01
description Fermentation of Alnus sibirica (AS) stems using Lactobacillus plantarum subsp. argentoratensis was conducted and three compounds isolated from the Alnus species were identified for the first time, 7-(3,4-dihydroxyphenyl)-1-(4-hydroxyphenyl)-heptan-3-one, 1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)-heptan-3-one and 4-(3,4-dihydroxyphenyl)-butan-2-one, along with 14 known compounds. The anti-oxidative and anti-inflammatory abilities of AS and fermented AS (FAS) as well as the isolated phenolic compounds from FAS were investigated. FAS showed stronger anti-oxidative and anti-inflammatory activities than non-fermented AS.
topic Alnus sibirica
fermentation
diarylheptanoid
url https://www.mdpi.com/1420-3049/22/9/1566
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AT minwonlee antiinflammatoryandantioxidativeactivitiesofphenoliccompoundsfromalnussibiricastemsfermentedbylactobacillusplantarumsubspargentoratensis
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