Chorioretinal Biopsy in an Immunocompromised Patient with Subretinal Mass
A 59-year-old woman with autoimmune diseases presented with rapidly decreased vision in the left eye. Clinical examination and investigations were inconclusive. Pars plana vitrectomy and chorioretinal biopsy were performed. The histopathologic examination revealed acute branching, septate hyphae mo...
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Mahidol University
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doaj-c29d246fab8a45fe8ce8d6ad8826644e2021-08-13T09:44:26ZengMahidol UniversitySiriraj Medical Journal2228-80822020-07-01623Chorioretinal Biopsy in an Immunocompromised Patient with Subretinal MassSomanus Thoongsuwan0 Nuttawut Rodanant1 Nattaporn Tesavibul2Mongkol Uiprasertkul3Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol UniversityDepartment of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol UniversityDepartment of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol UniversityDepartment of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University A 59-year-old woman with autoimmune diseases presented with rapidly decreased vision in the left eye. Clinical examination and investigations were inconclusive. Pars plana vitrectomy and chorioretinal biopsy were performed. The histopathologic examination revealed acute branching, septate hyphae morphologically consistent with Aspergillus spp. The infection responded to systemic and intravitreous voriconazole. The subretinal mass gradually subsided but eventually the eye became blind. Chorioretinal biopsy is a valuable diagnostic procedure which, in some cases, may be the only way to provide a definite diagnosis and specific treatment of patients with progressive chorioretinal lesions of unknown etiology. In the presented case, although the vision cannot be recovered, we can avoid unnecessary enucleation and prevent the spread of infection that may threaten patient’s life. https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/243769Chorioretinal biopsyfungal endophthalmitisaspergillus endophthalmitis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Somanus Thoongsuwan Nuttawut Rodanant Nattaporn Tesavibul Mongkol Uiprasertkul |
spellingShingle |
Somanus Thoongsuwan Nuttawut Rodanant Nattaporn Tesavibul Mongkol Uiprasertkul Chorioretinal Biopsy in an Immunocompromised Patient with Subretinal Mass Siriraj Medical Journal Chorioretinal biopsy fungal endophthalmitis aspergillus endophthalmitis |
author_facet |
Somanus Thoongsuwan Nuttawut Rodanant Nattaporn Tesavibul Mongkol Uiprasertkul |
author_sort |
Somanus Thoongsuwan |
title |
Chorioretinal Biopsy in an Immunocompromised Patient with Subretinal Mass |
title_short |
Chorioretinal Biopsy in an Immunocompromised Patient with Subretinal Mass |
title_full |
Chorioretinal Biopsy in an Immunocompromised Patient with Subretinal Mass |
title_fullStr |
Chorioretinal Biopsy in an Immunocompromised Patient with Subretinal Mass |
title_full_unstemmed |
Chorioretinal Biopsy in an Immunocompromised Patient with Subretinal Mass |
title_sort |
chorioretinal biopsy in an immunocompromised patient with subretinal mass |
publisher |
Mahidol University |
series |
Siriraj Medical Journal |
issn |
2228-8082 |
publishDate |
2020-07-01 |
description |
A 59-year-old woman with autoimmune diseases presented with rapidly decreased vision in the left eye. Clinical examination and investigations were inconclusive. Pars plana vitrectomy and chorioretinal biopsy were performed. The histopathologic examination revealed acute branching, septate hyphae morphologically consistent with Aspergillus spp. The infection responded to systemic and intravitreous voriconazole. The subretinal mass gradually subsided but eventually the eye became blind.
Chorioretinal biopsy is a valuable diagnostic procedure which, in some cases, may be the only way to provide a definite diagnosis and specific treatment of patients with progressive chorioretinal lesions of unknown etiology. In the presented case, although the vision cannot be recovered, we can avoid unnecessary enucleation and prevent the spread of infection that may threaten patient’s life.
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topic |
Chorioretinal biopsy fungal endophthalmitis aspergillus endophthalmitis |
url |
https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/243769 |
work_keys_str_mv |
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